Eruptive disseminated Spitz nevi - Case report,
Abstract Spitz nevus is a benign melanocytic lesion, which presents in several ways: solitary, agminated, or disseminated. The disseminated variant is uncommon; it may have a rapid evolution (the eruptive form) and be difficult to manage. This report presents the case of a 24-year-old patient with m...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Dermatologia
2020-03-01
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| Series: | Anais Brasileiros de Dermatologia |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962020000100071&tlng=en |
| _version_ | 1819285096696381440 |
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| author | Pablo Vargas Rodrigo Cárdenas Roberto Cullen Andrés Figueroa |
| author_facet | Pablo Vargas Rodrigo Cárdenas Roberto Cullen Andrés Figueroa |
| author_sort | Pablo Vargas |
| collection | DOAJ |
| description | Abstract Spitz nevus is a benign melanocytic lesion, which presents in several ways: solitary, agminated, or disseminated. The disseminated variant is uncommon; it may have a rapid evolution (the eruptive form) and be difficult to manage. This report presents the case of a 24-year-old patient with multiple papules on his limbs, which had appeared four years previously. On physical examination, 120 pink and skin-colored papules were seen, which under dermoscopy were observed to be homogeneous, pink vascular lesions. Histopathologic study revealed epithelioid cells arranged in groups or singly in the dermis and dermo-epidermal junction. They were HMB-45 positive in the superficial dermis, and Ki-67 < 1%. Given these findings, a diagnosis of eruptive disseminated Spitz nevi was made. |
| first_indexed | 2024-12-24T01:57:50Z |
| format | Article |
| id | doaj.art-c9252b18dcf243118cc213e803bc35b0 |
| institution | Directory Open Access Journal |
| issn | 0365-0596 |
| language | English |
| last_indexed | 2024-12-24T01:57:50Z |
| publishDate | 2020-03-01 |
| publisher | Sociedade Brasileira de Dermatologia |
| record_format | Article |
| series | Anais Brasileiros de Dermatologia |
| spelling | doaj.art-c9252b18dcf243118cc213e803bc35b02022-12-21T17:21:32ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962020-03-01951717410.1016/j.abd.2019.01.010Eruptive disseminated Spitz nevi - Case report,Pablo Vargashttps://orcid.org/0000-0002-9388-2940Rodrigo Cárdenashttps://orcid.org/0000-0003-4952-7842Roberto Cullenhttps://orcid.org/0000-0002-7661-4944Andrés Figueroahttps://orcid.org/0000-0002-7847-7605Abstract Spitz nevus is a benign melanocytic lesion, which presents in several ways: solitary, agminated, or disseminated. The disseminated variant is uncommon; it may have a rapid evolution (the eruptive form) and be difficult to manage. This report presents the case of a 24-year-old patient with multiple papules on his limbs, which had appeared four years previously. On physical examination, 120 pink and skin-colored papules were seen, which under dermoscopy were observed to be homogeneous, pink vascular lesions. Histopathologic study revealed epithelioid cells arranged in groups or singly in the dermis and dermo-epidermal junction. They were HMB-45 positive in the superficial dermis, and Ki-67 < 1%. Given these findings, a diagnosis of eruptive disseminated Spitz nevi was made.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962020000100071&tlng=enEpithelioid and spindle cellImmunohistochemistryNevi and melanomasNevus |
| spellingShingle | Pablo Vargas Rodrigo Cárdenas Roberto Cullen Andrés Figueroa Eruptive disseminated Spitz nevi - Case report, Anais Brasileiros de Dermatologia Epithelioid and spindle cell Immunohistochemistry Nevi and melanomas Nevus |
| title | Eruptive disseminated Spitz nevi - Case report, |
| title_full | Eruptive disseminated Spitz nevi - Case report, |
| title_fullStr | Eruptive disseminated Spitz nevi - Case report, |
| title_full_unstemmed | Eruptive disseminated Spitz nevi - Case report, |
| title_short | Eruptive disseminated Spitz nevi - Case report, |
| title_sort | eruptive disseminated spitz nevi case report |
| topic | Epithelioid and spindle cell Immunohistochemistry Nevi and melanomas Nevus |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962020000100071&tlng=en |
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