Cooperativity in RNA-Protein Interactions: Global Analysis of RNA Binding Specificity
The control and function of RNA are governed by the specificity of RNA binding proteins. Here, we describe a method for global unbiased analysis of RNA-protein interactions that uses in vitro selection, high-throughput sequencing, and sequence-specificity landscapes. The method yields affinities for...
Main Authors: | Zachary T. Campbell, Devesh Bhimsaria, Cary T. Valley, Jose A. Rodriguez-Martinez, Elena Menichelli, James R. Williamson, Aseem Z. Ansari, Marvin Wickens |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-05-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124712001167 |
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