Alveolar socket healing in 5-lipoxygenase knockout aged female mice treated or not with high dose of zoledronic acid

Alveolar socket healing in 5-lipoxygenase knockout aged female mice treated or not with high dose of zoledronic acid

Abstract This study investigated the role 5-lypoxigenase (5-LO) on alveolar socket healing in aged female mice treated with zoledronic acid (ZL). Forty 129/Sv female mice (64–68 weeks old), 20 wild type (WT) and 20 5-LO knockout (5LOKO) were equally distributed according to ZL treatment: WT Control,...

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Main Authors: Ramez H. Mahmoud, Claudia C. Biguetti, Gustavo B. Simionato, Isabela C. Custódio, Raquel B. P. Silva, Marco A. H. Duarte, Leonardo P. Faverani, Edilson Ervolino, Walid D. Fakhouri, Mariza A. Matsumoto
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98713-2

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