Adherence to healthy dietary pattern is associated with lower risk of multiple sclerosis
Background Different studies have confirmed the role of nutritional factors in the etiology of Multiple sclerosis (MS). However, dietary patterns associated with the risk of MS remain unknown. Objectives This study aimed to investigate the possible relationship between the existing dietary patterns...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2022-04-01
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| Series: | Journal of Central Nervous System Disease |
| Online Access: | https://doi.org/10.1177/11795735221092516 |
| _version_ | 1818206534532857856 |
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| author | Fatemeh Keykhaei Somayeh Norouzy Mohsen Froughipour Mohsen Nematy Morteza Saeidi Lida Jarahi Fatemeh Amiri Mahsa Malek Ahmadi Abdolreza Norouzy |
| author_facet | Fatemeh Keykhaei Somayeh Norouzy Mohsen Froughipour Mohsen Nematy Morteza Saeidi Lida Jarahi Fatemeh Amiri Mahsa Malek Ahmadi Abdolreza Norouzy |
| author_sort | Fatemeh Keykhaei |
| collection | DOAJ |
| description | Background Different studies have confirmed the role of nutritional factors in the etiology of Multiple sclerosis (MS). However, dietary patterns associated with the risk of MS remain unknown. Objectives This study aimed to investigate the possible relationship between the existing dietary patterns and the risk of MS. Methods This case-control study was conducted in Mashhad city, Iran in 2015. In total, 197 MS patients and 200 control subjects (matched in terms of age, gender, education level, and body mass index) were enrolled in this study. The required data were collected through interviews and questionnaire completion. Moreover, the data on the usual dietary intake of each participant during the past year were evaluated using a valid and reliable semi-quantitative food frequency questionnaire (160 items). Logistic regression analysis was applied to discover the associations between dietary patterns and the risk of MS. Results Four major dietary patterns were identified in this study, including Unhealthy, Western, Healthy, and Traditional. After adjustment for smoking habits, the family history of autoimmune diseases and the duration of breastfeeding, the highest tertile of Healthy dietary pattern was found to be associated with the reduced risk of MS by 74% (OR = .26; P < .001), whereas the Unhealthy dietary pattern was associated with a three-fold increased risk of MS (OR = 3.04; P < .001). However, no correlation was observed between the Western and Traditional dietary patterns and the risk of MS. Conclusion According to the results of this study, a healthy diet may reduce the risk of MS, whereas an unhealthy dietary pattern may. |
| first_indexed | 2024-12-12T04:14:33Z |
| format | Article |
| id | doaj.art-c92beebf4f8e4818951b4c841419fa40 |
| institution | Directory Open Access Journal |
| issn | 1179-5735 |
| language | English |
| last_indexed | 2024-12-12T04:14:33Z |
| publishDate | 2022-04-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Central Nervous System Disease |
| spelling | doaj.art-c92beebf4f8e4818951b4c841419fa402022-12-22T00:38:31ZengSAGE PublishingJournal of Central Nervous System Disease1179-57352022-04-011410.1177/11795735221092516Adherence to healthy dietary pattern is associated with lower risk of multiple sclerosisFatemeh KeykhaeiSomayeh NorouzyMohsen FroughipourMohsen NematyMorteza SaeidiLida JarahiFatemeh AmiriMahsa Malek AhmadiAbdolreza NorouzyBackground Different studies have confirmed the role of nutritional factors in the etiology of Multiple sclerosis (MS). However, dietary patterns associated with the risk of MS remain unknown. Objectives This study aimed to investigate the possible relationship between the existing dietary patterns and the risk of MS. Methods This case-control study was conducted in Mashhad city, Iran in 2015. In total, 197 MS patients and 200 control subjects (matched in terms of age, gender, education level, and body mass index) were enrolled in this study. The required data were collected through interviews and questionnaire completion. Moreover, the data on the usual dietary intake of each participant during the past year were evaluated using a valid and reliable semi-quantitative food frequency questionnaire (160 items). Logistic regression analysis was applied to discover the associations between dietary patterns and the risk of MS. Results Four major dietary patterns were identified in this study, including Unhealthy, Western, Healthy, and Traditional. After adjustment for smoking habits, the family history of autoimmune diseases and the duration of breastfeeding, the highest tertile of Healthy dietary pattern was found to be associated with the reduced risk of MS by 74% (OR = .26; P < .001), whereas the Unhealthy dietary pattern was associated with a three-fold increased risk of MS (OR = 3.04; P < .001). However, no correlation was observed between the Western and Traditional dietary patterns and the risk of MS. Conclusion According to the results of this study, a healthy diet may reduce the risk of MS, whereas an unhealthy dietary pattern may.https://doi.org/10.1177/11795735221092516 |
| spellingShingle | Fatemeh Keykhaei Somayeh Norouzy Mohsen Froughipour Mohsen Nematy Morteza Saeidi Lida Jarahi Fatemeh Amiri Mahsa Malek Ahmadi Abdolreza Norouzy Adherence to healthy dietary pattern is associated with lower risk of multiple sclerosis Journal of Central Nervous System Disease |
| title | Adherence to healthy dietary pattern is associated with lower risk of multiple sclerosis |
| title_full | Adherence to healthy dietary pattern is associated with lower risk of multiple sclerosis |
| title_fullStr | Adherence to healthy dietary pattern is associated with lower risk of multiple sclerosis |
| title_full_unstemmed | Adherence to healthy dietary pattern is associated with lower risk of multiple sclerosis |
| title_short | Adherence to healthy dietary pattern is associated with lower risk of multiple sclerosis |
| title_sort | adherence to healthy dietary pattern is associated with lower risk of multiple sclerosis |
| url | https://doi.org/10.1177/11795735221092516 |
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