A Perturbed Asymmetrical Y-TypeSheathless Chip for Particle Control Based on Adjustable Tilted-Angle Traveling Surface Acoustic Waves (ataTSAWs)
The precise control of target particles (20 µm) at different inclination angles <i>θ<sub>i</sub></i> is achieved by combining a perturbed asymmetric sheathless Y-type microchannel and a digital transducer (IDT). The offset single-row micropillar array with the buffer area can...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-08-01
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| Series: | Biosensors |
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| Online Access: | https://www.mdpi.com/2079-6374/12/8/611 |
| _version_ | 1827623518273011712 |
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| author | Junping Duan Miaomiao Ji Binzhen Zhang |
| author_facet | Junping Duan Miaomiao Ji Binzhen Zhang |
| author_sort | Junping Duan |
| collection | DOAJ |
| description | The precise control of target particles (20 µm) at different inclination angles <i>θ<sub>i</sub></i> is achieved by combining a perturbed asymmetric sheathless Y-type microchannel and a digital transducer (IDT). The offset single-row micropillar array with the buffer area can not only concentrate large and small particles in a fixed region of the flow channel, but also avoid the large deflection of some small particles at the end of the array. The addition of the buffer area can effectively improve the separation purity of the chip. By exploring the manufacturing process of the microchannel substrate, an adjustable tilted-angle scheme is proposed. The use of ataTSAW makes the acoustic field area in the microchannel have no corner effect region. Through experiments, when the signal source frequency was 33.6 MHz, and the flow rate was 20 µL/min, our designed chip could capture 20 µm particles when <i>θ<sub>i</sub></i> = 5°. The deflection of 20 µm particles can be realized when <i>θ<sub>i</sub></i> = 15°–45°. The precise dynamic separation of 20 µm particles can be achieved when <i>θ<sub>i</sub></i> = 25°–45°, and the separation purity and efficiency were 97% and 100%, respectively. |
| first_indexed | 2024-03-09T11:49:47Z |
| format | Article |
| id | doaj.art-c92c409b48fb4fa187f20b3aead2e3cd |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-09T11:49:47Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-c92c409b48fb4fa187f20b3aead2e3cd2023-11-30T23:17:12ZengMDPI AGBiosensors2079-63742022-08-0112861110.3390/bios12080611A Perturbed Asymmetrical Y-TypeSheathless Chip for Particle Control Based on Adjustable Tilted-Angle Traveling Surface Acoustic Waves (ataTSAWs)Junping Duan0Miaomiao Ji1Binzhen Zhang2Key Laboratory of Instrumentation Science & Dynamic Measurement, Ministry of Education, North University of China, Taiyuan 030051, ChinaKey Laboratory of Instrumentation Science & Dynamic Measurement, Ministry of Education, North University of China, Taiyuan 030051, ChinaKey Laboratory of Instrumentation Science & Dynamic Measurement, Ministry of Education, North University of China, Taiyuan 030051, ChinaThe precise control of target particles (20 µm) at different inclination angles <i>θ<sub>i</sub></i> is achieved by combining a perturbed asymmetric sheathless Y-type microchannel and a digital transducer (IDT). The offset single-row micropillar array with the buffer area can not only concentrate large and small particles in a fixed region of the flow channel, but also avoid the large deflection of some small particles at the end of the array. The addition of the buffer area can effectively improve the separation purity of the chip. By exploring the manufacturing process of the microchannel substrate, an adjustable tilted-angle scheme is proposed. The use of ataTSAW makes the acoustic field area in the microchannel have no corner effect region. Through experiments, when the signal source frequency was 33.6 MHz, and the flow rate was 20 µL/min, our designed chip could capture 20 µm particles when <i>θ<sub>i</sub></i> = 5°. The deflection of 20 µm particles can be realized when <i>θ<sub>i</sub></i> = 15°–45°. The precise dynamic separation of 20 µm particles can be achieved when <i>θ<sub>i</sub></i> = 25°–45°, and the separation purity and efficiency were 97% and 100%, respectively.https://www.mdpi.com/2079-6374/12/8/611asymmetric Y-type microchannelbuffer areaIDTadjustable tilted-angleparticle control |
| spellingShingle | Junping Duan Miaomiao Ji Binzhen Zhang A Perturbed Asymmetrical Y-TypeSheathless Chip for Particle Control Based on Adjustable Tilted-Angle Traveling Surface Acoustic Waves (ataTSAWs) Biosensors asymmetric Y-type microchannel buffer area IDT adjustable tilted-angle particle control |
| title | A Perturbed Asymmetrical Y-TypeSheathless Chip for Particle Control Based on Adjustable Tilted-Angle Traveling Surface Acoustic Waves (ataTSAWs) |
| title_full | A Perturbed Asymmetrical Y-TypeSheathless Chip for Particle Control Based on Adjustable Tilted-Angle Traveling Surface Acoustic Waves (ataTSAWs) |
| title_fullStr | A Perturbed Asymmetrical Y-TypeSheathless Chip for Particle Control Based on Adjustable Tilted-Angle Traveling Surface Acoustic Waves (ataTSAWs) |
| title_full_unstemmed | A Perturbed Asymmetrical Y-TypeSheathless Chip for Particle Control Based on Adjustable Tilted-Angle Traveling Surface Acoustic Waves (ataTSAWs) |
| title_short | A Perturbed Asymmetrical Y-TypeSheathless Chip for Particle Control Based on Adjustable Tilted-Angle Traveling Surface Acoustic Waves (ataTSAWs) |
| title_sort | perturbed asymmetrical y typesheathless chip for particle control based on adjustable tilted angle traveling surface acoustic waves atatsaws |
| topic | asymmetric Y-type microchannel buffer area IDT adjustable tilted-angle particle control |
| url | https://www.mdpi.com/2079-6374/12/8/611 |
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