The association between weight gain at different stages of pregnancy and risk of gestational diabetes mellitus
Abstract Aims/Introduction Women with excessive gestational weight gain (GWG) are at a higher risk for complications during pregnancy, such as preeclampsia. However, the association between excessive GWG and gestational diabetes mellitus (GDM) remains unclear. Materials and Methods We retrospectivel...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-02-01
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| Series: | Journal of Diabetes Investigation |
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| Online Access: | https://doi.org/10.1111/jdi.13648 |
| _version_ | 1818294851269033984 |
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| author | Ya‐Chun Chuang Lulu Huang Wan‐Ying Lee Steven W. Shaw Fu‐Ling Chu Tai‐Ho Hung |
| author_facet | Ya‐Chun Chuang Lulu Huang Wan‐Ying Lee Steven W. Shaw Fu‐Ling Chu Tai‐Ho Hung |
| author_sort | Ya‐Chun Chuang |
| collection | DOAJ |
| description | Abstract Aims/Introduction Women with excessive gestational weight gain (GWG) are at a higher risk for complications during pregnancy, such as preeclampsia. However, the association between excessive GWG and gestational diabetes mellitus (GDM) remains unclear. Materials and Methods We retrospectively reviewed 8,352 women from our obstetric database with singleton pregnancies who gave birth after 28 completed weeks of gestation between January 1, 2012, and December 31, 2016, excluding pregnancies complicated by fetal anomalies, fetal death, and overt diabetes. Diagnosis of GDM was based on the criteria recommended by the International Association of Diabetes and Pregnancy Study Groups. We used two classification methods to define excessive GWG: a weight gain above the 90th percentile of the population, or exceeding the upper range recommended by the Institute of Medicine, stratified by pre‐pregnancy body mass index. Statistical analysis was performed using multiple logistic regression to determine the association between excessive GWG and the risk of GDM. Results Overall, 1,129 women (13.5%) were diagnosed with GDM. There was no difference in GWG between women with and without GDM in the first trimester and before GDM screening. Women with GDM had significantly less GWG in the second trimester, after GDM screening, and throughout the whole gestation than women without GDM. No correlation was found between excessive GWG in the first and second trimesters, before GDM screening, and the later development of GDM. Conclusions Our results indicate that excessive GWG prior to GDM screening is not associated with an increased risk of GDM. |
| first_indexed | 2024-12-13T03:38:19Z |
| format | Article |
| id | doaj.art-c92c80dc2fc547d29663130568e82f74 |
| institution | Directory Open Access Journal |
| issn | 2040-1116 2040-1124 |
| language | English |
| last_indexed | 2024-12-13T03:38:19Z |
| publishDate | 2022-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Investigation |
| spelling | doaj.art-c92c80dc2fc547d29663130568e82f742022-12-22T00:00:59ZengWileyJournal of Diabetes Investigation2040-11162040-11242022-02-0113235936610.1111/jdi.13648The association between weight gain at different stages of pregnancy and risk of gestational diabetes mellitusYa‐Chun Chuang0Lulu Huang1Wan‐Ying Lee2Steven W. Shaw3Fu‐Ling Chu4Tai‐Ho Hung5Department of Obstetrics and Gynecology Taipei Chang Gung Memorial Hospital Taipei TaiwanDepartment of Obstetrics and Gynecology Taipei Chang Gung Memorial Hospital Taipei TaiwanDepartment of Nursing Linkou Chang Gung Memorial Hospital Taoyuan TaiwanDepartment of Obstetrics and Gynecology Taipei Chang Gung Memorial Hospital Taipei TaiwanDepartment of Nursing Chang Gung University of Science and Technology Taoyuan TaiwanDepartment of Obstetrics and Gynecology Taipei Chang Gung Memorial Hospital Taipei TaiwanAbstract Aims/Introduction Women with excessive gestational weight gain (GWG) are at a higher risk for complications during pregnancy, such as preeclampsia. However, the association between excessive GWG and gestational diabetes mellitus (GDM) remains unclear. Materials and Methods We retrospectively reviewed 8,352 women from our obstetric database with singleton pregnancies who gave birth after 28 completed weeks of gestation between January 1, 2012, and December 31, 2016, excluding pregnancies complicated by fetal anomalies, fetal death, and overt diabetes. Diagnosis of GDM was based on the criteria recommended by the International Association of Diabetes and Pregnancy Study Groups. We used two classification methods to define excessive GWG: a weight gain above the 90th percentile of the population, or exceeding the upper range recommended by the Institute of Medicine, stratified by pre‐pregnancy body mass index. Statistical analysis was performed using multiple logistic regression to determine the association between excessive GWG and the risk of GDM. Results Overall, 1,129 women (13.5%) were diagnosed with GDM. There was no difference in GWG between women with and without GDM in the first trimester and before GDM screening. Women with GDM had significantly less GWG in the second trimester, after GDM screening, and throughout the whole gestation than women without GDM. No correlation was found between excessive GWG in the first and second trimesters, before GDM screening, and the later development of GDM. Conclusions Our results indicate that excessive GWG prior to GDM screening is not associated with an increased risk of GDM.https://doi.org/10.1111/jdi.13648Gestational diabetes mellitusGestational weight gainBody mass index |
| spellingShingle | Ya‐Chun Chuang Lulu Huang Wan‐Ying Lee Steven W. Shaw Fu‐Ling Chu Tai‐Ho Hung The association between weight gain at different stages of pregnancy and risk of gestational diabetes mellitus Journal of Diabetes Investigation Gestational diabetes mellitus Gestational weight gain Body mass index |
| title | The association between weight gain at different stages of pregnancy and risk of gestational diabetes mellitus |
| title_full | The association between weight gain at different stages of pregnancy and risk of gestational diabetes mellitus |
| title_fullStr | The association between weight gain at different stages of pregnancy and risk of gestational diabetes mellitus |
| title_full_unstemmed | The association between weight gain at different stages of pregnancy and risk of gestational diabetes mellitus |
| title_short | The association between weight gain at different stages of pregnancy and risk of gestational diabetes mellitus |
| title_sort | association between weight gain at different stages of pregnancy and risk of gestational diabetes mellitus |
| topic | Gestational diabetes mellitus Gestational weight gain Body mass index |
| url | https://doi.org/10.1111/jdi.13648 |
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