Protective effect of rutin supplementation against cisplatin-induced Nephrotoxicity in rats

Protective effect of rutin supplementation against cisplatin-induced Nephrotoxicity in rats

Abstract Background Cisplatin (CP) is commonly used in the treatment of different types of cancer but nephrotoxicity has been a major limiting factor. Therefore, the present study aimed to study the possible protective effect of rutin against nephrotoxicity induced by cisplatin in rats. Methods Fort...

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Bibliographic Details
Main Authors: Ali R. Alhoshani, Mohamed M. Hafez, Sufia Husain, Abdel Malek Al-sheikh, Moureq R. Alotaibi, Salim S. Al Rejaie, Musaad A. Alshammari, Mashal M. Almutairi, Othman A. Al-Shabanah
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Nephrology
Subjects:
Cisplatin
Nephrotoxicity
P38 MAPK
Gene expression
Online Access:http://link.springer.com/article/10.1186/s12882-017-0601-y

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