Implications of Concurrent <i>IDH1</i> and <i>IDH2</i> Mutations on Survival in Glioma—A Case Report and Systematic Review

Implications of Concurrent <i>IDH1</i> and <i>IDH2</i> Mutations on Survival in Glioma—A Case Report and Systematic Review

Both <i>IDH1</i> (isocitrate dehydrogenase 1) and <i>IDH2</i> (isocitrate dehydrogenase 2) mutations play a vital role in the development of gliomas through disruption of normal cellular metabolic processes. Here we describe a case of a patient with an IDH-mutant astrocytoma,...

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Bibliographic Details
Main Authors: Alexander Yuile, Laveniya Satgunaseelan, Joe Wei, Marina Kastelan, Michael F. Back, Maggie Lee, Heng Wei, Michael E. Buckland, Adrian Lee, Helen R. Wheeler
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Current Issues in Molecular Biology
Subjects:
<i>IDH1</i>
<i>IDH2</i>
glioma
astrocytoma
next generation sequencing
Online Access:https://www.mdpi.com/1467-3045/44/10/348

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https://www.mdpi.com/1467-3045/44/10/348

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