Adjunctive Plasma Rich in Growth Factors in the Treatment of Osteomyelitis and Large Odontogenic Cysts Prior to Successful Implant Rehabilitation: Case Report
Osteomyelitis of the jaws presents a clinical challenge to conventional treatment, often requiring multiple surgical interventions resulting in significant deformity and presenting significant problems to satisfactory rehabilitation. While benign odontogenic cysts, such as the radicular cyst, are ge...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Dentistry Journal |
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| Online Access: | https://www.mdpi.com/2304-6767/11/8/184 |
| _version_ | 1797585069314932736 |
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| author | Marc DuVal Mohammad Hamdan Alkhraisat |
| author_facet | Marc DuVal Mohammad Hamdan Alkhraisat |
| author_sort | Marc DuVal |
| collection | DOAJ |
| description | Osteomyelitis of the jaws presents a clinical challenge to conventional treatment, often requiring multiple surgical interventions resulting in significant deformity and presenting significant problems to satisfactory rehabilitation. While benign odontogenic cysts, such as the radicular cyst, are generally predictably treated, they can cause significant localized bone destruction and thus can present significant problems in satisfactory rehabilitation. In this case report, patients were treated combining conventionally appropriate surgical debridement and oral antibiotics with adjunctive plasma rich in growth factors (PRGF). Patients showed a complete soft tissue and osseous regeneration to their pre-pathologic state, with successful implant rehabilitation. PRGF appears to be highly successful in minimizing or eliminating osseous deformities normally associated with conventional treatment of osteomyelitis of the jaw and treatment of large odontogenic cysts. Future trials must be performed to confirm these results in comparison to controls using conventional treatment alone. |
| first_indexed | 2024-03-11T00:00:35Z |
| format | Article |
| id | doaj.art-c9348ca9ddce46bcac6e6a04013c8a6c |
| institution | Directory Open Access Journal |
| issn | 2304-6767 |
| language | English |
| last_indexed | 2024-03-11T00:00:35Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Dentistry Journal |
| spelling | doaj.art-c9348ca9ddce46bcac6e6a04013c8a6c2023-11-19T00:47:07ZengMDPI AGDentistry Journal2304-67672023-07-0111818410.3390/dj11080184Adjunctive Plasma Rich in Growth Factors in the Treatment of Osteomyelitis and Large Odontogenic Cysts Prior to Successful Implant Rehabilitation: Case ReportMarc DuVal0Mohammad Hamdan Alkhraisat1Department of Dentistry, McGill University, Montreal, QC H3A 0C7, CanadaRegenerative Medicine Department, BTI Biotechnology Institute, 01007 Vitoria, SpainOsteomyelitis of the jaws presents a clinical challenge to conventional treatment, often requiring multiple surgical interventions resulting in significant deformity and presenting significant problems to satisfactory rehabilitation. While benign odontogenic cysts, such as the radicular cyst, are generally predictably treated, they can cause significant localized bone destruction and thus can present significant problems in satisfactory rehabilitation. In this case report, patients were treated combining conventionally appropriate surgical debridement and oral antibiotics with adjunctive plasma rich in growth factors (PRGF). Patients showed a complete soft tissue and osseous regeneration to their pre-pathologic state, with successful implant rehabilitation. PRGF appears to be highly successful in minimizing or eliminating osseous deformities normally associated with conventional treatment of osteomyelitis of the jaw and treatment of large odontogenic cysts. Future trials must be performed to confirm these results in comparison to controls using conventional treatment alone.https://www.mdpi.com/2304-6767/11/8/184tissue engineeringbone regenerationplatelet-rich plasmaosteomyelitisodontogenic cystsosseous pathology |
| spellingShingle | Marc DuVal Mohammad Hamdan Alkhraisat Adjunctive Plasma Rich in Growth Factors in the Treatment of Osteomyelitis and Large Odontogenic Cysts Prior to Successful Implant Rehabilitation: Case Report Dentistry Journal tissue engineering bone regeneration platelet-rich plasma osteomyelitis odontogenic cysts osseous pathology |
| title | Adjunctive Plasma Rich in Growth Factors in the Treatment of Osteomyelitis and Large Odontogenic Cysts Prior to Successful Implant Rehabilitation: Case Report |
| title_full | Adjunctive Plasma Rich in Growth Factors in the Treatment of Osteomyelitis and Large Odontogenic Cysts Prior to Successful Implant Rehabilitation: Case Report |
| title_fullStr | Adjunctive Plasma Rich in Growth Factors in the Treatment of Osteomyelitis and Large Odontogenic Cysts Prior to Successful Implant Rehabilitation: Case Report |
| title_full_unstemmed | Adjunctive Plasma Rich in Growth Factors in the Treatment of Osteomyelitis and Large Odontogenic Cysts Prior to Successful Implant Rehabilitation: Case Report |
| title_short | Adjunctive Plasma Rich in Growth Factors in the Treatment of Osteomyelitis and Large Odontogenic Cysts Prior to Successful Implant Rehabilitation: Case Report |
| title_sort | adjunctive plasma rich in growth factors in the treatment of osteomyelitis and large odontogenic cysts prior to successful implant rehabilitation case report |
| topic | tissue engineering bone regeneration platelet-rich plasma osteomyelitis odontogenic cysts osseous pathology |
| url | https://www.mdpi.com/2304-6767/11/8/184 |
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