Massively Parallel CRISPR‐Based Genetic Perturbation Screening at Single‐Cell Resolution

Massively Parallel CRISPR‐Based Genetic Perturbation Screening at Single‐Cell Resolution

Abstract The clustered regularly interspaced short palindromic repeats (CRISPR)‐based genetic screening has been demonstrated as a powerful approach for unbiased functional genomics research. Single‐cell CRISPR screening (scCRISPR) techniques, which result from the combination of single‐cell toolkit...

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Bibliographic Details
Main Authors: Junyun Cheng, Gaole Lin, Tianhao Wang, Yunzhu Wang, Wenbo Guo, Jie Liao, Penghui Yang, Jie Chen, Xin Shao, Xiaoyan Lu, Ling Zhu, Yi Wang, Xiaohui Fan
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:Advanced Science
Subjects:
CRISPR/Cas
genetic screening
imaging‐based phenotyping
multiplexed perturbations
single‐cell sequencing
Online Access:https://doi.org/10.1002/advs.202204484

Internet

https://doi.org/10.1002/advs.202204484

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