Paeoniflorin Attenuates Limb Ischemia by Promoting Angiogenesis Through ERα/ROCK-2 Pathway

Paeoniflorin Attenuates Limb Ischemia by Promoting Angiogenesis Through ERα/ROCK-2 Pathway

<b>Background:</b> Peripheral artery disease (PAD) is a high-risk vascular condition, and vascular remodeling has become a promising therapeutic approach. Paeoniflorin (PF) is the main bioactive compound in the roots of <i>Paeonia lactiflora</i> Pall, which is commonly used t...

Full description

Bibliographic Details
Main Authors: Mengyao Li, Qianyi Wang, Sinan Zhu, Wei Sun, Xiuyun Ren, Zhenkun Xu, Xinze Li, Shaoxia Wang, Qi Liu, Lu Chen, Hong Wang
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Pharmaceuticals
Subjects:
paeoniflorin
hind limb ischemia
angiogenesis
endothelial cells
inflammation
ERα/ROCK-2 pathway
Online Access:https://www.mdpi.com/1424-8247/18/2/272

Internet

https://www.mdpi.com/1424-8247/18/2/272

Similar Items