Identification of PDCD1 as a potential biomarker in acute rejection after kidney transplantation via comprehensive bioinformatic analysis

Identification of PDCD1 as a potential biomarker in acute rejection after kidney transplantation via comprehensive bioinformatic analysis

BackgroundAcute rejection is a determinant of prognosis following kidney transplantation. It is essential to search for novel noninvasive biomarkers for early diagnosis and prompt treatment.MethodsGene microarray data was downloaded from the Gene Expression Omnibus (GEO) expression profile database...

Full description

Bibliographic Details
Main Authors:	Yucheng Wang, Xiaoli Lin, Cuili Wang, Xinyu Liu, Xiaoying Wu, Yingying Qiu, Ying Chen, Qin Zhou, Haige Zhao, Jianghua Chen, Hongfeng Huang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Series:	Frontiers in Immunology
Subjects:	acute rejection PDCD1 kidney transplantation biomarker immune infiltration weighted gene co-expression network analysis
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.1076546/full

Similar Items

STXBP3 and GOT2 predict immunological activity in acute allograft rejection
by: Qinfan Yao, et al.
Published: (2022-12-01)

Preliminary Investigation of the Biomarkers of Acute Renal Transplant Rejection Using Integrated Proteomics Studies, Gene Expression Omnibus Datasets, and RNA Sequencing
by: Shuai Han, et al.
Published: (2022-05-01)

Successful pregnancies in post-kidney transplant couples: four case reports
by: Hao Huang, et al.
Published: (2023-07-01)

SLAMF8 Participates in Acute Renal Transplant Rejection via TLR4 Pathway on Pro-Inflammatory Macrophages
by: Lisha Teng, et al.
Published: (2022-04-01)

Case Report: Pathogenic MYH9 c.5797delC Mutation in a Patient With Apparent Thrombocytopenia and Nephropathy
by: Pingping Ren, et al.
Published: (2021-07-01)

A promising natural killer cell-based model and a nomogram for the prognostic prediction of clear-cell renal cell carcinoma
by: Qinfan Yao, et al.
Published: (2024-01-01)

Integrated genomic, transcriptomic and metabolomic analysis reveals MDH2 mutation-induced metabolic disorder in recurrent focal segmental glomerulosclerosis
by: Qixia Shen, et al.
Published: (2022-09-01)

Pre-transplant Transcriptional Signature in Peripheral Blood Mononuclear Cells of Acute Renal Allograft Rejection
by: Wenyu Xiang, et al.
Published: (2022-01-01)

Comprehensive analysis of a tryptophan metabolism-related model in the prognostic prediction and immune status for clear cell renal carcinoma
by: Qinfan Yao, et al.
Published: (2024-01-01)

Artificial urinary biomarkers for early diagnosis of acute renal allograft rejection
by: Cheng, Penghui, et al.
Published: (2023)

Identification of VCAN as Hub Gene for Diabetic Kidney Disease Immune Injury Using Integrated Bioinformatics Analysis
by: Qiannan Xu, et al.
Published: (2021-09-01)

The Mitochondria-Targeted Metabolic Tubular Injury in Diabetic Kidney Disease
by: Hong Jiang, et al.
Published: (2019-02-01)

Serum Metabolomics Benefits Discrimination Kidney Disease Development in Type 2 Diabetes Patients
by: Xiaofeng Peng, et al.
Published: (2022-05-01)

SDF4 Is a Prognostic Factor for 28-Days Mortality in Patients With Sepsis via Negatively Regulating ER Stress
by: Tingting Zhu, et al.
Published: (2021-07-01)

Brucellosis in kidney transplant donor: A case report
by: Shuaihui Liu, et al.
Published: (2022-09-01)

Telomere shortening in patients on long-term hemodialysis
by: Yucheng Wang, et al.
Published: (2021-12-01)

Role of Age-Related Changes in DNA Methylation in the Disproportionate Susceptibility and Worse Outcomes of Sepsis in Older Adults
by: Xiabing Lang, et al.
Published: (2022-02-01)

Down-Regulation of PDCD4 Promotes Proliferation, Angiogenesis and Tumorigenesis in Glioma Cells
by: Guo Pin, et al.
Published: (2020-11-01)

Corrigendum: Lymphatic reconstruction in kidney allograft aggravates chronic rejection by promoting alloantigen presentation
by: Jinwen Lin, et al.
Published: (2022-11-01)

Lymphatic Reconstruction in Kidney Allograft Aggravates Chronic Rejection by Promoting Alloantigen Presentation
by: Jinwen Lin, et al.
Published: (2021-12-01)

PDCD6 cooperates with C-Raf to facilitate colorectal cancer progression via Raf/MEK/ERK activation
by: Xiaojuan Wang, et al.
Published: (2020-08-01)

MicroRNA-16 Promotes Ovarian Granulosa Cell Proliferation and Suppresses Apoptosis Through Targeting PDCD4 in Polycystic Ovarian Syndrome
by: Xiafei Fu, et al.
Published: (2018-07-01)

Corrigendum to “Lipopolysaccharide-induced podocyte injury is regulated by calcineurin/NFAT and TLR4/MyD88/NF-κB signaling pathways through Angiopoietin-like protein 4” [Genes Dis DOI: 10.1016/j.gendis.2020.07.005]
by: Xiujin Shen, et al.
Published: (2022-03-01)

Lipopolysaccharide-induced podocyte injury is regulated by calcineurin/NFAT and TLR4/MyD88/NF-κB signaling pathways through angiopoietin-like protein 4
by: Xiujin Shen, et al.
Published: (2022-03-01)

Corrigendum to “Lipopolysaccharide-induced podocyte injury is regulated by calcineurin/NFAT and TLR4/MyD88/NF-κB signaling pathways through Angiopoietin-like protein 4” [Genes & Diseases 9(2022) 443–455]
by: Xiujin Shen, et al.
Published: (2022-11-01)

Dendritic Cells: Versatile Players in Renal Transplantation
by: Jinwen Lin, et al.
Published: (2021-05-01)

Serum Matrix Metalloproteinase-7 Level is Associated with Fibrosis and Renal Survival in Patients with IgA Nephropathy
by: Jian Zhang, et al.
Published: (2017-09-01)

Inhibiting DNA Methylation Improves Survival in Severe Sepsis by Regulating NF-κB Pathway
by: Luxi Cao, et al.
Published: (2020-07-01)

DTL promotes cancer progression by PDCD4 ubiquitin-dependent degradation
by: Haoran Cui, et al.
Published: (2019-08-01)

Transcript Engineered Extracellular Vesicles Alleviate Alloreactive Dynamics in Renal Transplantation
by: Jinwen Lin, et al.
Published: (2022-11-01)

Exploring the Bio-Functional Effect of Single Nucleotide Polymorphisms in the Promoter Region of the TNFSF4, CD28, and PDCD1 Genes
by: Ding-Ping Chen, et al.
Published: (2023-03-01)

The Dual Role of PDCD10 in Cancers: A Promising Therapeutic Target
by: Jingdian Liu, et al.
Published: (2022-12-01)

Overexpression of miR-21 in stem cells improves ovarian structure and function in rats with chemotherapy-induced ovarian damage by targeting PDCD4 and PTEN to inhibit granulosa cell apoptosis
by: Xiafei Fu, et al.
Published: (2017-08-01)

Complete mitochondrial genome and phylogenetic analysis of Stonogobiops yasha (Perciformes, Gobiidae)
by: Hengtong Qiu, et al.
Published: (2019-07-01)

PDCD5 as a Potential Biomarker for Improved Prediction of the Incidence and Remission for Patients with Rheumatoid Arthritis
by: Juan Xiao, et al.
Published: (2023-08-01)

Induction of Myocardial PDCD4 in Coronary Microembolization-Related Cardiac Dysfunction: Evidence from a Large-Animal Study
by: Qiang Su, et al.
Published: (2014-08-01)

miR-21a inhibits decidual cell apoptosis by targeting Pdcd4
by: Rong Li, et al.
Published: (2021-03-01)

miR-181b functions as an oncomiR in colorectal cancer by targeting PDCD4
by: Yanqing Liu, et al.
Published: (2016-09-01)

RNA: A Reject Neighbors Algorithm for Influence Maximization in Complex Networks
by: Dongqi Wang, et al.
Published: (2020-08-01)

SKP2 promotes breast cancer tumorigenesis and radiation tolerance through PDCD4 ubiquitination
by: Ce Li, et al.
Published: (2019-02-01)