CAPE and Neuroprotection: A Review

CAPE and Neuroprotection: A Review

Propolis, a product of the honey bee, has been used in traditional medicine for many years. A hydrophobic bioactive polyphenolic ester, caffeic acid phenethyl ester (CAPE), is one of the most extensively investigated active components of propolis. Several studies have indicated that CAPE has a broad...

Full description

Bibliographic Details
Main Authors:	Marwa Balaha, Barbara De Filippis, Amelia Cataldi, Viviana di Giacomo
Format:	Article
Language:	English
Published:	MDPI AG 2021-01-01
Series:	Biomolecules
Subjects:	caffeic acid phenethyl ester (CAPE) neuroprotection neurodegenerative disease propolis CNS injury CNS ischemia
Online Access:	https://www.mdpi.com/2218-273X/11/2/176

Similar Items

The Pluripotent Activities of Caffeic Acid Phenethyl Ester
by: Batoryna Olgierd, et al.
Published: (2021-03-01)

Caffeic Acid Phenethyl Ester (CAPE) Synergistically Enhances Paclitaxel Activity in Ovarian Cancer Cells
by: Anna Kleczka, et al.
Published: (2023-08-01)

Ethanolic Extract of Propolis and CAPE as Cardioprotective Agents against LPS and IFN-α Stressed Cardiovascular Injury
by: Anna Kurek-Górecka, et al.
Published: (2024-02-01)

Caffeic Acid Phenethyl Ester (CAPE): Biosynthesis, Derivatives and Formulations with Neuroprotective Activities
by: Rebeca Pérez, et al.
Published: (2023-07-01)

Effect of Propolis on moderate persistent asthma: A phase two randomized, double blind, controlled clinical trial
by: Majid Mirsadraee, et al.
Published: (2021-01-01)

Caffeic Acid Phenethyl Ester and Ethanol Extract of Propolis Induce the Complementary Cytotoxic Effect on Triple-Negative Breast Cancer Cell Lines
by: Anna Rzepecka-Stojko, et al.
Published: (2015-05-01)

Identification of Caffeic Acid Phenethyl Ester (CAPE) as a Potent Neurodifferentiating Natural Compound That Improves Cognitive and Physiological Functions in Animal Models of Neurodegenerative Diseases
by: Arpita Konar, et al.
Published: (2020-11-01)

Caffeic Acid Phenethyl Ester (CAPE) Induced Apoptosis in Serous Ovarian Cancer OV7 Cells by Deregulation of BCL2/BAX Genes
by: Anna Kleczka, et al.
Published: (2020-07-01)

Experimental Evidence for Therapeutic Potentials of Propolis
by: Priyanshu Bhargava, et al.
Published: (2021-07-01)

Protective Effect of Caffeic Acid Phenethyl Ester in Rat Cerebral Ischemia/Reperfusion Damage
by: Ertuğrul Uzar, et al.
Published: (2011-09-01)

Protective Effect of Caffeic Acid Phenethyl Ester in Rat Cerebral Ischemia/Reperfusion Damage
by: Ertuğrul Uzar, et al.
Published: (2011-09-01)

The Phenolic Profile and Anti-Inflammatory Effect of Ethanolic Extract of Polish Propolis on Activated Human Gingival Fibroblasts-1 Cell Line
by: Anna Kurek-Górecka, et al.
Published: (2023-11-01)

The impact of caffeic acid phenethyl ester, chrysin and ethanolic extracts of propolis on PLD1 gene expression in AGS cell line
by: Hamideh Jafari-Ghahfarokhi, et al.
Published: (2019-10-01)

A Low Dose Combination of Withaferin A and Caffeic Acid Phenethyl Ester Possesses Anti-Metastatic Potential In Vitro: Molecular Targets and Mechanisms
by: Anissa Nofita Sari, et al.
Published: (2022-02-01)

Caffeic Acid Phenethyl Ester Reduces the Adverse Effects of Nicotine on the Endometrium
by: Amin Namdari, et al.
Published: (2023-09-01)

In Vitro Activity of Caffeic Acid Phenethyl Ester against Different Oral Microorganisms
by: Rasha AlSheikh, et al.
Published: (2022-04-01)

Research progress on synthesis and application of caffeic acid phenethyl ester in propolis
by: Meimei ZHANG, et al.
Published: (2020-12-01)

The Anti-Biofilm Efficacy of Caffeic Acid Phenethyl Ester (CAPE) In Vitro and a Murine Model of Oral Candidiasis
by: Patrícia Pimentel de Barros, et al.
Published: (2021-08-01)

In Vitro Antimicrobial Potential of CAPE and Caffeamide Derivatives against Oral Microbes
by: Yin-Hwa Shih, et al.
Published: (2022-04-01)

CAPE-pNO2 Inhibited the Growth and Metastasis of Triple-Negative Breast Cancer via the EGFR/STAT3/Akt/E-Cadherin Signaling Pathway
by: Qin Huang, et al.
Published: (2019-06-01)

Ethanol extract of propolis and its constituent caffeic acid phenethyl ester inhibit breast cancer cells proliferation in inflammatory microenvironment by inhibiting TLR4 signal pathway and inducing apoptosis and autophagy
by: Huasong Chang, et al.
Published: (2017-09-01)

Promising influences of caffeic acid and caffeic acid phenethyl ester against natural and chemical toxins: A comprehensive and mechanistic review
by: Sajjad Ehtiati, et al.
Published: (2023-08-01)

Caffeic Acid Phenethyl Ester Protects Kidney Mitochondria against Ischemia/Reperfusion Induced Injury in an <i>In Vivo</i> Rat Model
by: Justina Kamarauskaite, et al.
Published: (2021-05-01)

Bone resorption, matrix metalloproteinases and caffeic acid phenethyl ester
by: Sumeyya Akyol, et al.
Published: (2016-12-01)

The Immunoregulatory Effects of Caffeic Acid Phenethyl Ester on the Cytokine Secretion of Peripheral Blood Mononuclear Cells From Asthmatic Children
by: Leticia Bautista Sy, et al.
Published: (2011-12-01)

Phenolic acid phenethylesters and their corresponding ketones: Inhibition of 5‐lipoxygenase and stability in human blood and HepaRG cells
by: Maroua Mbarik, et al.
Published: (2019-10-01)

Ameliorating Role of Caffeic Acid Phenethyl Ester (CAPE) Against Methotrexate-Induced Oxidative Stress in the Sciatic Nerve, Spinal Cord and Brain Stem Tissues of Rats
by: Ertuğrul Uzar, et al.
Published: (2010-03-01)

Ameliorating Role of Caffeic Acid Phenethyl Ester (CAPE) Against Methotrexate-Induced Oxidative Stress in the Sciatic Nerve, Spinal Cord and Brain Stem Tissues of Rats
by: Ertuğrul Uzar, et al.
Published: (2010-03-01)

Caffeic Acid Phenethyl Ester Assisted by Reversible Electroporation—In Vitro Study on Human Melanoma Cells
by: Anna Choromanska, et al.
Published: (2020-05-01)

Analysis of potential protective effects of caffeic acid phenethyl ester against gentamicin ototoxicity: An experimental study
by: Fuat Aydemir, et al.
Published: (2022-01-01)

Editorial: Factors affecting boar sperm preservation and quality
by: Elisabeth Pinart, et al.
Published: (2023-07-01)

Caffeic Acid Phenethyl Ester (CAPE) Inhibits Cross-Kingdom Biofilm Formation of Streptococcus mutans and Candida albicans
by: Wumeng Yin, et al.
Published: (2022-10-01)

Caffeic Acid Phenethyl Ester With Mesenchymal Stem Cells Improves Behavioral and Histopathological Changes in the Rat Model of Parkinson Disease
by: Khojasteh Rahimi Jaberi, et al.
Published: (2022-09-01)

Effects of Temperature, Metal Ions and Biosurfactants on Interaction Mechanism between Caffeic Acid Phenethyl Ester and Hemoglobin
by: Yutong Li, et al.
Published: (2023-04-01)

Caffeic acid phenethyl ester inhibits MDA-MB-231 cell proliferation in inflammatory microenvironment by suppressing glycolysis and lipid metabolism
by: Qian Wu, et al.
Published: (2023-12-01)

The protective effect of caffeic acid phenethyl ester in the nephrotoxicity induced by α-cypermethrin
by: Nur Gokhan, et al.
Published: (2023-08-01)

Caffeic acid phenethyl ester attenuates neuropathic pain by suppressing the p38/NF-κB signal pathway in microglia
by: Cheng H, et al.
Published: (2018-11-01)

The intervention of caffeamide derivative K36 from intestine to brain
by: Chin‐Kun Wang
Published: (2020-03-01)

Attenuating effects of caffeic acid phenethyl ester with intralipid on hepatotoxicity of chlorpyrifos in the case of rats
by: Recep Dokuyucu, et al.
Published: (2016-12-01)

Caffeic acid phenethyl ester suppresses androgen receptor signaling and stability via inhibition of phosphorylation on Ser81 and Ser213
by: Ying-Yu Kuo, et al.
Published: (2019-08-01)