Salubrinal Ameliorates Inflammation and Neovascularization via the Caspase 3/Enos Signaling in an Alkaline-Induced Rat Corneal Neovascularization Model

Salubrinal Ameliorates Inflammation and Neovascularization via the Caspase 3/Enos Signaling in an Alkaline-Induced Rat Corneal Neovascularization Model

<i>Background and Objectives:</i> Ocular alkaline burn is a clinical emergency that can cause permanent vision loss due to limbal stem cell deficiency and corneal neovascularization (CNV). Although the basic pathogenetic mechanisms are considered to be acute oxidative stress and corneal...

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Bibliographic Details
Main Authors: Gokhan Ozge, Umut Karaca, Mehtap Savran, Gulsah Usta, Kanat Gulle, Murat Sevimli, Fatma Nihan Cankara, Halil Asci
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Medicina
Subjects:
apoptosis
corneal injury
inflammation
endoplasmic reticulum stress
eNOS
Online Access:https://www.mdpi.com/1648-9144/59/2/323

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