Age-based spatial disparities of COVID-19 incidence rates in the United States counties

COVID-19 incidence disparities have been documented in the literature, but the different driving factors among age groups have yet to be explicitly explained. This study proposes a community-based COVID-19 spatial disparity model, considering different levels of geographic units (individual and comm...

Full description

Bibliographic Details
Main Author: Qian Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249835/?tool=EBI
_version_ 1797806999807721472
author Qian Huang
author_facet Qian Huang
author_sort Qian Huang
collection DOAJ
description COVID-19 incidence disparities have been documented in the literature, but the different driving factors among age groups have yet to be explicitly explained. This study proposes a community-based COVID-19 spatial disparity model, considering different levels of geographic units (individual and community), various contextual variables, multiple COVID-19 outcomes, and different geographic contextual elements. The model assumes the existence of age nonstationarity effects on health determinants, suggesting that health effects of contextual variables vary among place and age groups. Based on this conceptual model and theory, the study selected 62 county-level variables for 1,748 U.S. counties during the pandemic, and created an Adjustable COVID-19 Potential Exposure Index (ACOVIDPEI) using principal component analysis (PCA). The validation was done with 71,521,009 COVID-19 patients in the U.S. from January 2020 through June 2022, with high incidence rates shifting from the Midwest, South Carolina, North Carolina, Arizona, and Tennessee to the West and East coasts. This study corroborates the age nonstationarity effect of health determinants on COVID-19 exposures. These results empirically identify the geographic disparities of COVID-19 incidence rates among age groups and provide the evidentiary guide for targeting pandemic recovery, mitigation, and preparedness in communities.
first_indexed 2024-03-13T06:15:55Z
format Article
id doaj.art-c9464ad961ce43c0b92fbb5c9e840f0f
institution Directory Open Access Journal
issn 1932-6203
language English
last_indexed 2024-03-13T06:15:55Z
publishDate 2023-01-01
publisher Public Library of Science (PLoS)
record_format Article
series PLoS ONE
spelling doaj.art-c9464ad961ce43c0b92fbb5c9e840f0f2023-06-11T05:31:30ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-01186Age-based spatial disparities of COVID-19 incidence rates in the United States countiesQian HuangCOVID-19 incidence disparities have been documented in the literature, but the different driving factors among age groups have yet to be explicitly explained. This study proposes a community-based COVID-19 spatial disparity model, considering different levels of geographic units (individual and community), various contextual variables, multiple COVID-19 outcomes, and different geographic contextual elements. The model assumes the existence of age nonstationarity effects on health determinants, suggesting that health effects of contextual variables vary among place and age groups. Based on this conceptual model and theory, the study selected 62 county-level variables for 1,748 U.S. counties during the pandemic, and created an Adjustable COVID-19 Potential Exposure Index (ACOVIDPEI) using principal component analysis (PCA). The validation was done with 71,521,009 COVID-19 patients in the U.S. from January 2020 through June 2022, with high incidence rates shifting from the Midwest, South Carolina, North Carolina, Arizona, and Tennessee to the West and East coasts. This study corroborates the age nonstationarity effect of health determinants on COVID-19 exposures. These results empirically identify the geographic disparities of COVID-19 incidence rates among age groups and provide the evidentiary guide for targeting pandemic recovery, mitigation, and preparedness in communities.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249835/?tool=EBI
spellingShingle Qian Huang
Age-based spatial disparities of COVID-19 incidence rates in the United States counties
PLoS ONE
title Age-based spatial disparities of COVID-19 incidence rates in the United States counties
title_full Age-based spatial disparities of COVID-19 incidence rates in the United States counties
title_fullStr Age-based spatial disparities of COVID-19 incidence rates in the United States counties
title_full_unstemmed Age-based spatial disparities of COVID-19 incidence rates in the United States counties
title_short Age-based spatial disparities of COVID-19 incidence rates in the United States counties
title_sort age based spatial disparities of covid 19 incidence rates in the united states counties
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249835/?tool=EBI
work_keys_str_mv AT qianhuang agebasedspatialdisparitiesofcovid19incidenceratesintheunitedstatescounties