Determination of cognitive domain involvement in a sample of patients diagnosed with schizophrenia and cardiovascular risk factors
Introduction Schizophrenia it’s a deteriorating illness, where the cognitive impairment it’s one of the predominant components in this process. Theory of neurodevelopment, the most widely recognized, explains that cognition will depend most of it, on premorbid development. However, other factors e...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2021-04-01
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| Series: | European Psychiatry |
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| Online Access: | https://www.cambridge.org/core/product/identifier/S0924933821014401/type/journal_article |
| _version_ | 1797617303300341760 |
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| author | J. García Eslava A. Marzán Gutierrez N. Riera Molist S. Escoté Llobet Q. Foguet-Boreu |
| author_facet | J. García Eslava A. Marzán Gutierrez N. Riera Molist S. Escoté Llobet Q. Foguet-Boreu |
| author_sort | J. García Eslava |
| collection | DOAJ |
| description |
Introduction
Schizophrenia it’s a deteriorating illness, where the cognitive impairment it’s one of the predominant components in this process. Theory of neurodevelopment, the most widely recognized, explains that cognition will depend most of it, on premorbid development. However, other factors explain this impairment, such as the cardiovascular risk factors (CVRF).
Objectives
The purpose of this study is to determine cognitive impairment and the domains affected in a sample of patients who suffered schizophrenia and almost one CVRF.
Methods
Cross-sectional study. Patients diagnosed with schizophrenia and at least one poorly controlled CVRF (diabetes, hypercholesterolemia, arterial hypertension or active smoking) were selected. Screen for Cognitive Impairment in Psychiatry (SCIP) scale was used to evaluate cognitive impairment and the domains affected.
Results
Preliminary data of twenty patients were included (60% men, mean age: 50 years). At CVRF in the sample, no diabetes was found, 75% had hypercholesterolemia, 15% arterial hypertension and 20% active smoking. SCIP scale showed deficits in word learning and delayed learning in 95% of the sample (n=19). The domain less affected was verbal fluency, affected in 55% of the sample (n=11). Additionally, moderate to severe cognitive impairment was observed in 65% of the sample (n=13).
Conclusions
More than half of the patients with schizophrenia and CVRF have a moderate to severe cognitive impairment. Intervention at CVRF could reduce the severity of cognitive impairment, improving functionality in these patients.
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| first_indexed | 2024-03-11T07:53:55Z |
| format | Article |
| id | doaj.art-c9477fa9f2c24599af67c1e8a7a20b77 |
| institution | Directory Open Access Journal |
| issn | 0924-9338 1778-3585 |
| language | English |
| last_indexed | 2024-03-11T07:53:55Z |
| publishDate | 2021-04-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | European Psychiatry |
| spelling | doaj.art-c9477fa9f2c24599af67c1e8a7a20b772023-11-17T05:06:11ZengCambridge University PressEuropean Psychiatry0924-93381778-35852021-04-0164S540S54010.1192/j.eurpsy.2021.1440Determination of cognitive domain involvement in a sample of patients diagnosed with schizophrenia and cardiovascular risk factorsJ. García Eslava0A. Marzán Gutierrez1N. Riera Molist2S. Escoté Llobet3Q. Foguet-Boreu4Mental Health Department, Consorci Hositalari Vic, Vic, SpainMental Health Department, Consorci Hospitalari de Vic, Vic, SpainMental Health Department, Consorci Hospitalari de Vic, Vic, SpainMental Health Department, Consorci Hospitalari de Vic, Vic, SpainMental Health Department, Consorci Hositalari Vic, Vic, Spain Introduction Schizophrenia it’s a deteriorating illness, where the cognitive impairment it’s one of the predominant components in this process. Theory of neurodevelopment, the most widely recognized, explains that cognition will depend most of it, on premorbid development. However, other factors explain this impairment, such as the cardiovascular risk factors (CVRF). Objectives The purpose of this study is to determine cognitive impairment and the domains affected in a sample of patients who suffered schizophrenia and almost one CVRF. Methods Cross-sectional study. Patients diagnosed with schizophrenia and at least one poorly controlled CVRF (diabetes, hypercholesterolemia, arterial hypertension or active smoking) were selected. Screen for Cognitive Impairment in Psychiatry (SCIP) scale was used to evaluate cognitive impairment and the domains affected. Results Preliminary data of twenty patients were included (60% men, mean age: 50 years). At CVRF in the sample, no diabetes was found, 75% had hypercholesterolemia, 15% arterial hypertension and 20% active smoking. SCIP scale showed deficits in word learning and delayed learning in 95% of the sample (n=19). The domain less affected was verbal fluency, affected in 55% of the sample (n=11). Additionally, moderate to severe cognitive impairment was observed in 65% of the sample (n=13). Conclusions More than half of the patients with schizophrenia and CVRF have a moderate to severe cognitive impairment. Intervention at CVRF could reduce the severity of cognitive impairment, improving functionality in these patients. https://www.cambridge.org/core/product/identifier/S0924933821014401/type/journal_articleschizophréniacognitive impairmentcognitive domainscardiovascular risk |
| spellingShingle | J. García Eslava A. Marzán Gutierrez N. Riera Molist S. Escoté Llobet Q. Foguet-Boreu Determination of cognitive domain involvement in a sample of patients diagnosed with schizophrenia and cardiovascular risk factors European Psychiatry schizophrénia cognitive impairment cognitive domains cardiovascular risk |
| title | Determination of cognitive domain involvement in a sample of patients diagnosed with schizophrenia and cardiovascular risk factors |
| title_full | Determination of cognitive domain involvement in a sample of patients diagnosed with schizophrenia and cardiovascular risk factors |
| title_fullStr | Determination of cognitive domain involvement in a sample of patients diagnosed with schizophrenia and cardiovascular risk factors |
| title_full_unstemmed | Determination of cognitive domain involvement in a sample of patients diagnosed with schizophrenia and cardiovascular risk factors |
| title_short | Determination of cognitive domain involvement in a sample of patients diagnosed with schizophrenia and cardiovascular risk factors |
| title_sort | determination of cognitive domain involvement in a sample of patients diagnosed with schizophrenia and cardiovascular risk factors |
| topic | schizophrénia cognitive impairment cognitive domains cardiovascular risk |
| url | https://www.cambridge.org/core/product/identifier/S0924933821014401/type/journal_article |
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