Transoral Incisionless Fundoplication for Refractory Gastroesophageal Reflux Disease: Where Do We Stand?

Gastroesophageal reflux disease (GERD) is a chronic, progressive, and costly medical condition affecting a substantial proportion of the world population, predominantly the Western population. The available treatment options for patients with refractory GERD symptoms are limited to either laparoscop...

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Main Authors: Deepanshu Jain, Shashideep Singhal
Format: Article
Language:English
Published: Korean Society of Gastrointestinal Endoscopy 2016-03-01
Series:Clinical Endoscopy
Subjects:
Online Access:http://www.e-ce.org/upload/pdf/ce-2015-044.pdf
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author Deepanshu Jain
Shashideep Singhal
author_facet Deepanshu Jain
Shashideep Singhal
author_sort Deepanshu Jain
collection DOAJ
description Gastroesophageal reflux disease (GERD) is a chronic, progressive, and costly medical condition affecting a substantial proportion of the world population, predominantly the Western population. The available treatment options for patients with refractory GERD symptoms are limited to either laparoscopic surgery with significant sequelae or potentially lifelong, high-dose proton pump inhibitor therapy. The restoration of the antireflux competence of the gastroesophageal junction at the anatomic and physiologic levels is critical for the effective long-term treatment of GERD. Transoral incisionless fundoplication (TIF) surgery is a safe, well-tolerated, and effective treatment that has yielded significant symptomatic improvement in patients with medically refractory GERD symptoms. In this review article, we have summarized case series and reports describing the role of TIF for patients with gastroesophageal reflux symptoms. The reported indications, techniques, complications, and success rates are also discussed.
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spelling doaj.art-c947c289f39e4cf39299fc4692dbb4462023-11-02T04:14:50ZengKorean Society of Gastrointestinal EndoscopyClinical Endoscopy2234-24002234-24432016-03-0149214715610.5946/ce.2015.0446834Transoral Incisionless Fundoplication for Refractory Gastroesophageal Reflux Disease: Where Do We Stand?Deepanshu Jain0Shashideep Singhal1 Department of Internal Medicine, Albert Einstein Medical Center, Philadelphia, PA, USA Division of Gastroenterology, Hepatology and Nutrition, University of Texas Health Science Center at Houston, Houston, TX, USAGastroesophageal reflux disease (GERD) is a chronic, progressive, and costly medical condition affecting a substantial proportion of the world population, predominantly the Western population. The available treatment options for patients with refractory GERD symptoms are limited to either laparoscopic surgery with significant sequelae or potentially lifelong, high-dose proton pump inhibitor therapy. The restoration of the antireflux competence of the gastroesophageal junction at the anatomic and physiologic levels is critical for the effective long-term treatment of GERD. Transoral incisionless fundoplication (TIF) surgery is a safe, well-tolerated, and effective treatment that has yielded significant symptomatic improvement in patients with medically refractory GERD symptoms. In this review article, we have summarized case series and reports describing the role of TIF for patients with gastroesophageal reflux symptoms. The reported indications, techniques, complications, and success rates are also discussed.http://www.e-ce.org/upload/pdf/ce-2015-044.pdfEndoscopic fundoplicationGastroesophageal refluxProton pump inhibitors
spellingShingle Deepanshu Jain
Shashideep Singhal
Transoral Incisionless Fundoplication for Refractory Gastroesophageal Reflux Disease: Where Do We Stand?
Clinical Endoscopy
Endoscopic fundoplication
Gastroesophageal reflux
Proton pump inhibitors
title Transoral Incisionless Fundoplication for Refractory Gastroesophageal Reflux Disease: Where Do We Stand?
title_full Transoral Incisionless Fundoplication for Refractory Gastroesophageal Reflux Disease: Where Do We Stand?
title_fullStr Transoral Incisionless Fundoplication for Refractory Gastroesophageal Reflux Disease: Where Do We Stand?
title_full_unstemmed Transoral Incisionless Fundoplication for Refractory Gastroesophageal Reflux Disease: Where Do We Stand?
title_short Transoral Incisionless Fundoplication for Refractory Gastroesophageal Reflux Disease: Where Do We Stand?
title_sort transoral incisionless fundoplication for refractory gastroesophageal reflux disease where do we stand
topic Endoscopic fundoplication
Gastroesophageal reflux
Proton pump inhibitors
url http://www.e-ce.org/upload/pdf/ce-2015-044.pdf
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