Association of ABO blood type with mortality in hospitalized patients with COVID-19
Objective: To explore the relation between ABO blood group system and in-hospital mortality in Mexican patients admitted with COVID-19.Materials and methods: We performed a retrospective study with 2,369 hospitalized patients with confirmed SARS-CoV-2 infection in a tertiary referral hospital, admit...
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| Format: | Article |
| Language: | English |
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Universidad Juárez Autónoma de Tabasco
2021-10-01
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| Series: | Horizonte Sanitario |
| Subjects: | |
| Online Access: | https://revistas.ujat.mx/index.php/horizonte/article/view/4516 |
| _version_ | 1797987216158359552 |
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| author | Eira Cerda-Reyes Arcelia Carolina Barrón-Campos José Antonio Almeyda-Farfán Cruz Vargas de León |
| author_facet | Eira Cerda-Reyes Arcelia Carolina Barrón-Campos José Antonio Almeyda-Farfán Cruz Vargas de León |
| author_sort | Eira Cerda-Reyes |
| collection | DOAJ |
| description | Objective: To explore the relation between ABO blood group system and in-hospital mortality in Mexican patients admitted with COVID-19.Materials and methods: We performed a retrospective study with 2,369 hospitalized patients with confirmed SARS-CoV-2 infection in a tertiary referral hospital, admitted between March 27 and December 10, 2020. Data were obtained from electronic health records. Adjusted and unadjusted Cox Proportional-Hazard models were performed to test the association of ABO blood groups with mortality of COVID-19 patients. The variables considered for adjustment of the models were age, sex, and main comorbidities.Results: Out of all studied patients, group O was the most frequent blood type with 1999 patients (84.3%), followed by group A (11.3%), B (3.5%) and AB (0.72%). Blood group A was associated with a lower hazard of death among COVID-19 patients compared with group O (adjusted HR = 0.72, 95% IC 0.55-0.95, P = 0.02. Groups B, AB and Positive Rh were not significantly associated with the outcome.Conclusions: We found evidence of a statistically significant association between ABO blood type and COVID-19 in-hospital death. Patients with blood group A may be less likely to die during hospitalization compared with group O |
| first_indexed | 2024-04-11T07:45:24Z |
| format | Article |
| id | doaj.art-c9486b876d5b4860b14aede59d64446b |
| institution | Directory Open Access Journal |
| issn | 1665-3262 2007-7459 |
| language | English |
| last_indexed | 2024-04-11T07:45:24Z |
| publishDate | 2021-10-01 |
| publisher | Universidad Juárez Autónoma de Tabasco |
| record_format | Article |
| series | Horizonte Sanitario |
| spelling | doaj.art-c9486b876d5b4860b14aede59d64446b2022-12-22T04:36:20ZengUniversidad Juárez Autónoma de TabascoHorizonte Sanitario1665-32622007-74592021-10-012111724https://doi.org/10.19136/hs.a21n1.4516Association of ABO blood type with mortality in hospitalized patients with COVID-19Eira Cerda-Reyes0https://orcid.org/0000-0003-1288-888XArcelia Carolina Barrón-Campos1https://orcid.org/0000-0002-3360-9029José Antonio Almeyda-Farfán2https://orcid.org/0000-0002-3928-9441Cruz Vargas de León3https://orcid.org/0000-0001-9428-3619Secretaria de la Defensa Nacional. Ciudad de México, México.Secretaria de la Defensa Nacional. Ciudad de México, México.Secretaria de la Defensa Nacional. Ciudad de México, México.Hospital Juárez de México. Ciudad de México, MéxicoObjective: To explore the relation between ABO blood group system and in-hospital mortality in Mexican patients admitted with COVID-19.Materials and methods: We performed a retrospective study with 2,369 hospitalized patients with confirmed SARS-CoV-2 infection in a tertiary referral hospital, admitted between March 27 and December 10, 2020. Data were obtained from electronic health records. Adjusted and unadjusted Cox Proportional-Hazard models were performed to test the association of ABO blood groups with mortality of COVID-19 patients. The variables considered for adjustment of the models were age, sex, and main comorbidities.Results: Out of all studied patients, group O was the most frequent blood type with 1999 patients (84.3%), followed by group A (11.3%), B (3.5%) and AB (0.72%). Blood group A was associated with a lower hazard of death among COVID-19 patients compared with group O (adjusted HR = 0.72, 95% IC 0.55-0.95, P = 0.02. Groups B, AB and Positive Rh were not significantly associated with the outcome.Conclusions: We found evidence of a statistically significant association between ABO blood type and COVID-19 in-hospital death. Patients with blood group A may be less likely to die during hospitalization compared with group Ohttps://revistas.ujat.mx/index.php/horizonte/article/view/4516covid-19blood group antigenmortalityprognos |
| spellingShingle | Eira Cerda-Reyes Arcelia Carolina Barrón-Campos José Antonio Almeyda-Farfán Cruz Vargas de León Association of ABO blood type with mortality in hospitalized patients with COVID-19 Horizonte Sanitario covid-19 blood group antigen mortality prognos |
| title | Association of ABO blood type with mortality in hospitalized patients with COVID-19 |
| title_full | Association of ABO blood type with mortality in hospitalized patients with COVID-19 |
| title_fullStr | Association of ABO blood type with mortality in hospitalized patients with COVID-19 |
| title_full_unstemmed | Association of ABO blood type with mortality in hospitalized patients with COVID-19 |
| title_short | Association of ABO blood type with mortality in hospitalized patients with COVID-19 |
| title_sort | association of abo blood type with mortality in hospitalized patients with covid 19 |
| topic | covid-19 blood group antigen mortality prognos |
| url | https://revistas.ujat.mx/index.php/horizonte/article/view/4516 |
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