Evaluating the neuroprotective effects of progesterone receptors on experimental traumatic brain injury: The PI3K/Akt pathway

Evaluating the neuroprotective effects of progesterone receptors on experimental traumatic brain injury: The PI3K/Akt pathway

Abstract Background Studies have confirmed the salutary effects of progesterone (P4) on traumatic brain injury (TBI). This study investigated the beneficial effects of P4 via its receptors on TBI, and also whether progesterone receptors (PRs) can modulate TBI through PI3K/Akt pathway. Material and m...

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Bibliographic Details
Main Authors: Ladan Amirkhosravi, Mohammad khaksari, Sedigheh Amiresmaili, Mojgan Sanjari, Parisa Khorasani, Morteza Hashemian
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Brain and Behavior
Subjects:
neuroprotection
oxidative stress
PI3K/p‐Akt
progesterone receptor
pro‐inflammatory cytokines
traumatic brain injury
Online Access:https://doi.org/10.1002/brb3.3244

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