Association of healthy lifestyle with incident cardiovascular diseases among hypertensive and normotensive Chinese adults
BackgroundWhether lifestyle improvement benefits in reducing cardiovascular diseases (CVD) events extend to hypertensive patients and whether these benefits differ between hypertensive and normotensive individuals is unclear. This study aimed to investigate the associations of an overall healthy lif...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-03-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1046943/full |
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| author | Jian Su Houyue Geng Lulu Chen Xikang Fan Jinyi Zhou Ming Wu Yan Lu Yujie Hua Jianrong Jin Yu Guo Jun Lv Jun Lv Pei Pei Zhengming Chen Ran Tao Ran Tao |
| author_facet | Jian Su Houyue Geng Lulu Chen Xikang Fan Jinyi Zhou Ming Wu Yan Lu Yujie Hua Jianrong Jin Yu Guo Jun Lv Jun Lv Pei Pei Zhengming Chen Ran Tao Ran Tao |
| author_sort | Jian Su |
| collection | DOAJ |
| description | BackgroundWhether lifestyle improvement benefits in reducing cardiovascular diseases (CVD) events extend to hypertensive patients and whether these benefits differ between hypertensive and normotensive individuals is unclear. This study aimed to investigate the associations of an overall healthy lifestyle with the subsequent development of CVD among participants with hypertension and normotension.MethodsUsing data from the Suzhou subcohort of the China Kadoorie Biobank study of 51,929 participants, this study defined five healthy lifestyle factors as nonsmoking or quitting for reasons other than illness; nonexcessive alcohol intake; relatively higher physical activity level; a relatively healthy diet; and having a standard waist circumference and body mass index. We estimated the associations of these lifestyle factors with CVD, ischemic heart disease (IHD) and ischemic stroke (IS).ResultsDuring a follow-up of 10.1 years, this study documented 6,151 CVD incidence events, 1,304 IHD incidence events, and 2,243 IS incidence events. Compared to those with 0–1 healthy lifestyle factors, HRs for those with 4–5 healthy factors were 0.71 (95% CI: 0.62, 0.81) for CVD, 0.56 (95% CI: 0.42, 0.75) for IHD, and 0.63 (95% CI: 0.51, 0.79) for IS among hypertensive participants. However, we did not observe this association among normotensive participants. Stratified analyses showed that the association between a healthy lifestyle and IHD risk was stronger among younger participants, and the association with IS risk was stronger among hypertensive individuals with lower household incomes.ConclusionAdherence to a healthy lifestyle pattern is associated with a lower risk of cardiovascular diseases among hypertensive patients, but this benefit is not as pronounced among normotensive patients. |
| first_indexed | 2024-04-10T06:22:01Z |
| format | Article |
| id | doaj.art-c94e0da849294f558c719beb3f7b3a33 |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-04-10T06:22:01Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-c94e0da849294f558c719beb3f7b3a332023-03-02T04:35:35ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2023-03-011010.3389/fcvm.2023.10469431046943Association of healthy lifestyle with incident cardiovascular diseases among hypertensive and normotensive Chinese adultsJian Su0Houyue Geng1Lulu Chen2Xikang Fan3Jinyi Zhou4Ming Wu5Yan Lu6Yujie Hua7Jianrong Jin8Yu Guo9Jun Lv10Jun Lv11Pei Pei12Zhengming Chen13Ran Tao14Ran Tao15Department of Noncommunicable Chronic Disease and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, ChinaDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, ChinaDepartment of Noncommunicable Chronic Disease and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, ChinaDepartment of Noncommunicable Chronic Disease and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, ChinaDepartment of Noncommunicable Chronic Disease and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, ChinaDepartment of Noncommunicable Chronic Disease and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, ChinaDepartment of Noncommunicable Chronic Disease Control and Prevention, Suzhou City Center for Disease Control and Prevention, Suzhou, ChinaDepartment of Noncommunicable Chronic Disease Control and Prevention, Suzhou City Center for Disease Control and Prevention, Suzhou, ChinaWuzhong District of Suzhou City Center for Disease Control and Prevention, Suzhou, ChinaFuwai Hospital Chinese Academy of Medical Sciences, Beijing, ChinaDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, ChinaPeking University Center for Public Health and Epidemic Preparedness and Response, Beijing, ChinaPeking University Center for Public Health and Epidemic Preparedness and Response, Beijing, ChinaClinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United KingdomDepartment of Noncommunicable Chronic Disease and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, ChinaDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, ChinaBackgroundWhether lifestyle improvement benefits in reducing cardiovascular diseases (CVD) events extend to hypertensive patients and whether these benefits differ between hypertensive and normotensive individuals is unclear. This study aimed to investigate the associations of an overall healthy lifestyle with the subsequent development of CVD among participants with hypertension and normotension.MethodsUsing data from the Suzhou subcohort of the China Kadoorie Biobank study of 51,929 participants, this study defined five healthy lifestyle factors as nonsmoking or quitting for reasons other than illness; nonexcessive alcohol intake; relatively higher physical activity level; a relatively healthy diet; and having a standard waist circumference and body mass index. We estimated the associations of these lifestyle factors with CVD, ischemic heart disease (IHD) and ischemic stroke (IS).ResultsDuring a follow-up of 10.1 years, this study documented 6,151 CVD incidence events, 1,304 IHD incidence events, and 2,243 IS incidence events. Compared to those with 0–1 healthy lifestyle factors, HRs for those with 4–5 healthy factors were 0.71 (95% CI: 0.62, 0.81) for CVD, 0.56 (95% CI: 0.42, 0.75) for IHD, and 0.63 (95% CI: 0.51, 0.79) for IS among hypertensive participants. However, we did not observe this association among normotensive participants. Stratified analyses showed that the association between a healthy lifestyle and IHD risk was stronger among younger participants, and the association with IS risk was stronger among hypertensive individuals with lower household incomes.ConclusionAdherence to a healthy lifestyle pattern is associated with a lower risk of cardiovascular diseases among hypertensive patients, but this benefit is not as pronounced among normotensive patients.https://www.frontiersin.org/articles/10.3389/fcvm.2023.1046943/fullhealthy lifestylecardiovascular diseasesischemic heart diseasestrokehypertensionprospective cohort study |
| spellingShingle | Jian Su Houyue Geng Lulu Chen Xikang Fan Jinyi Zhou Ming Wu Yan Lu Yujie Hua Jianrong Jin Yu Guo Jun Lv Jun Lv Pei Pei Zhengming Chen Ran Tao Ran Tao Association of healthy lifestyle with incident cardiovascular diseases among hypertensive and normotensive Chinese adults Frontiers in Cardiovascular Medicine healthy lifestyle cardiovascular diseases ischemic heart disease stroke hypertension prospective cohort study |
| title | Association of healthy lifestyle with incident cardiovascular diseases among hypertensive and normotensive Chinese adults |
| title_full | Association of healthy lifestyle with incident cardiovascular diseases among hypertensive and normotensive Chinese adults |
| title_fullStr | Association of healthy lifestyle with incident cardiovascular diseases among hypertensive and normotensive Chinese adults |
| title_full_unstemmed | Association of healthy lifestyle with incident cardiovascular diseases among hypertensive and normotensive Chinese adults |
| title_short | Association of healthy lifestyle with incident cardiovascular diseases among hypertensive and normotensive Chinese adults |
| title_sort | association of healthy lifestyle with incident cardiovascular diseases among hypertensive and normotensive chinese adults |
| topic | healthy lifestyle cardiovascular diseases ischemic heart disease stroke hypertension prospective cohort study |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1046943/full |
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