Reversible Tau Phosphorylation Induced by Synthetic Torpor in the Spinal Cord of the Rat

Reversible Tau Phosphorylation Induced by Synthetic Torpor in the Spinal Cord of the Rat

Tau is a key protein in neurons, where it affects the dynamics of the microtubule system. The hyperphosphorylation of Tau (PP-Tau) commonly leads to the formation of neurofibrillary tangles, as it occurs in tauopathies, a group of neurodegenerative diseases, including Alzheimer's. Hypothermia-r...

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Bibliographic Details
Main Authors: Timna Hitrec, Fabio Squarcio, Matteo Cerri, Davide Martelli, Alessandra Occhinegro, Emiliana Piscitiello, Domenico Tupone, Roberto Amici, Marco Luppi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Neuroanatomy
Subjects:
hypothermia
hibernation
microglia
tauopathies
GSK3β
motor neurons
Online Access:https://www.frontiersin.org/articles/10.3389/fnana.2021.592288/full

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