"Intravenous Magnesium Sulfate as an adjunct in the treatment of severe Asthmatic patients non-responding to conventional therapy "
Treatment of acute asthma is based on rapid reversal of bronchospasm and arresting airway inflammation. This study was done to determine the effect of intravenous MgSO4 for improvement of pulmonary fuction in patients with acute asthma non-responding to routine therapy. This randomized, double –blin...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
2001-12-01
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| Series: | Acta Medica Iranica |
| Subjects: | |
| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/2480 |
| _version_ | 1828304547275079680 |
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| author | Bijani KH Moghadamnia AA Islami Khalili E |
| author_facet | Bijani KH Moghadamnia AA Islami Khalili E |
| author_sort | Bijani KH |
| collection | DOAJ |
| description | Treatment of acute asthma is based on rapid reversal of bronchospasm and arresting airway inflammation. This study was done to determine the effect of intravenous MgSO4 for improvement of pulmonary fuction in patients with acute asthma non-responding to routine therapy. This randomized, double –blind controlled study was conducted on 48 patients, magnesium sulfate group , n=48 aged 12-85 years, 26 men, 22 women, and control (saline) group, n=33, aged 15-80 years, 17 men, 16 women, who had not responded to routine treatment. Peak expiratory flow rate (PEFR) was done before MgSO4 (25 mg/kg) and normal saline (100 ml) as a baseline criteria and after infusion of drugs at 30 mm and 3 hr. All patients were also given bronchodilators. The main outcome was PEER. Data were analyzed by X2 and t-test and differences between each point, were considered significant at P |
| first_indexed | 2024-04-13T14:13:37Z |
| format | Article |
| id | doaj.art-c95236587ea249499fffd468c43e9c21 |
| institution | Directory Open Access Journal |
| issn | 0044-6025 1735-9694 |
| language | English |
| last_indexed | 2024-04-13T14:13:37Z |
| publishDate | 2001-12-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-c95236587ea249499fffd468c43e9c212022-12-22T02:43:43ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942001-12-01394"Intravenous Magnesium Sulfate as an adjunct in the treatment of severe Asthmatic patients non-responding to conventional therapy " Bijani KH0 Moghadamnia AA1 Islami Khalili E2 Treatment of acute asthma is based on rapid reversal of bronchospasm and arresting airway inflammation. This study was done to determine the effect of intravenous MgSO4 for improvement of pulmonary fuction in patients with acute asthma non-responding to routine therapy. This randomized, double –blind controlled study was conducted on 48 patients, magnesium sulfate group , n=48 aged 12-85 years, 26 men, 22 women, and control (saline) group, n=33, aged 15-80 years, 17 men, 16 women, who had not responded to routine treatment. Peak expiratory flow rate (PEFR) was done before MgSO4 (25 mg/kg) and normal saline (100 ml) as a baseline criteria and after infusion of drugs at 30 mm and 3 hr. All patients were also given bronchodilators. The main outcome was PEER. Data were analyzed by X2 and t-test and differences between each point, were considered significant at Phttps://acta.tums.ac.ir/index.php/acta/article/view/2480Acute asthmaNon-respondingMagnesium sulfate (MgSO4)Peak expiratory flow rate (PEER) |
| spellingShingle | Bijani KH Moghadamnia AA Islami Khalili E "Intravenous Magnesium Sulfate as an adjunct in the treatment of severe Asthmatic patients non-responding to conventional therapy " Acta Medica Iranica Acute asthma Non-responding Magnesium sulfate (MgSO4) Peak expiratory flow rate (PEER) |
| title | "Intravenous Magnesium Sulfate as an adjunct in the treatment of severe Asthmatic patients non-responding to conventional therapy " |
| title_full | "Intravenous Magnesium Sulfate as an adjunct in the treatment of severe Asthmatic patients non-responding to conventional therapy " |
| title_fullStr | "Intravenous Magnesium Sulfate as an adjunct in the treatment of severe Asthmatic patients non-responding to conventional therapy " |
| title_full_unstemmed | "Intravenous Magnesium Sulfate as an adjunct in the treatment of severe Asthmatic patients non-responding to conventional therapy " |
| title_short | "Intravenous Magnesium Sulfate as an adjunct in the treatment of severe Asthmatic patients non-responding to conventional therapy " |
| title_sort | intravenous magnesium sulfate as an adjunct in the treatment of severe asthmatic patients non responding to conventional therapy |
| topic | Acute asthma Non-responding Magnesium sulfate (MgSO4) Peak expiratory flow rate (PEER) |
| url | https://acta.tums.ac.ir/index.php/acta/article/view/2480 |
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