Domains of Physical Activity in Relation to Stiffness Index in the General Population
Background Regular exercise training represents an important modifier of arterial stiffness (AS). Therefore, sex‐specific relations between domains of physical activity (PA; commuting, domestic, and leisure‐time PA, including active sport and occupational PA) with AS were investigated. Methods and R...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-08-01
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| Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| Subjects: | |
| Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.121.020930 |
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| author | Natalie Arnold Arne Deiseroth Omar Hahad Simon Diestelmeier Andreas Schulz Andrea Daubenbüchel Tommaso Gori Harald Binder Norbert Pfeiffer Jürgen Prochaska Manfred Beutel Karl J. Lackner Thomas Münzel Philipp S. Wild |
| author_facet | Natalie Arnold Arne Deiseroth Omar Hahad Simon Diestelmeier Andreas Schulz Andrea Daubenbüchel Tommaso Gori Harald Binder Norbert Pfeiffer Jürgen Prochaska Manfred Beutel Karl J. Lackner Thomas Münzel Philipp S. Wild |
| author_sort | Natalie Arnold |
| collection | DOAJ |
| description | Background Regular exercise training represents an important modifier of arterial stiffness (AS). Therefore, sex‐specific relations between domains of physical activity (PA; commuting, domestic, and leisure‐time PA, including active sport and occupational PA) with AS were investigated. Methods and Results Stiffness index by digital photoplethysmography was investigated in 12 650 subjects from the GHS (Gutenberg Health Study). Self‐reported PA was evaluated by the “Short Questionnaire to Assess Health‐Enhancing Physical Activity” and reported as activity score peer week, being a combined measure of duration, frequency, and intensity of PA. Multivariable linear regression analysis demonstrated strong beneficial effects of repetitive activities, such as active commuting or leisure‐time PA–related walking on AS in men, but not in women. Lower AS associated with endurance training was also found among men and premenopausal women. In contrast, intense occupational PA was related to stiffer vessels in men (P<0.0001) and women (P=0.0021) in a fully adjusted model. Combination of both, performing endurance training and having stiffness index values below median, resulted in the best survival. In contrast, subjects with elevated stiffness index at baseline without any endurance activities demonstrated the worst survival. Conclusions In this population representative sample, a differential impact of domains of self‐reported PA on AS was demonstrated. Our data strengthen the importance of regular endurance PA to induce a reduction of AS, which, in turn, may improve cardiovascular prognosis. We also report deleterious effects of intense occupational PA on stiffness index, a finding that needs further confirmation by larger prospective trials. |
| first_indexed | 2024-03-13T07:05:52Z |
| format | Article |
| id | doaj.art-c9571ec6f8b74be2b8a172a5023cea7c |
| institution | Directory Open Access Journal |
| issn | 2047-9980 |
| language | English |
| last_indexed | 2024-03-13T07:05:52Z |
| publishDate | 2021-08-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| spelling | doaj.art-c9571ec6f8b74be2b8a172a5023cea7c2023-06-06T12:10:51ZengWileyJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease2047-99802021-08-01101610.1161/JAHA.121.020930Domains of Physical Activity in Relation to Stiffness Index in the General PopulationNatalie Arnold0Arne Deiseroth1Omar Hahad2Simon Diestelmeier3Andreas Schulz4Andrea Daubenbüchel5Tommaso Gori6Harald Binder7Norbert Pfeiffer8Jürgen Prochaska9Manfred Beutel10Karl J. Lackner11Thomas Münzel12Philipp S. Wild13Department of Cardiology Cardiology I, University Medical Center of the Johannes Gutenberg‐University Mainz Mainz GermanyDepartment of Sport, Exercise and Health University of Basel SwitzerlandDepartment of Cardiology Cardiology I, University Medical Center of the Johannes Gutenberg‐University Mainz Mainz GermanyDepartment of Cardiology Cardiology I, University Medical Center of the Johannes Gutenberg‐University Mainz Mainz GermanyDepartment of Cardiology Preventive Cardiology and Preventive Medicine University Medical Center of the Johannes Gutenberg‐University Mainz Mainz GermanyDepartment of Cardiology Preventive Cardiology and Preventive Medicine University Medical Center of the Johannes Gutenberg‐University Mainz Mainz GermanyDepartment of Cardiology Cardiology I, University Medical Center of the Johannes Gutenberg‐University Mainz Mainz GermanyInstitute of Medical Biostatistics, Epidemiology and Informatics (IMBEI)University Medical Center of the Johannes Gutenberg‐University Mainz Mainz GermanyDepartment of Ophthalmology University Medical Center of the Johannes Gutenberg‐University Mainz Mainz GermanyDepartment of Cardiology Cardiology I, University Medical Center of the Johannes Gutenberg‐University Mainz Mainz GermanyDepartment of Psychosomatic Medicine and Psychotherapy University Medical Center of the Johannes Gutenberg‐University Mainz Mainz GermanyDZHK (German Center for Cardiovascular Research) Partner Site Rhine‐Main Mainz GermanyDepartment of Cardiology Cardiology I, University Medical Center of the Johannes Gutenberg‐University Mainz Mainz GermanyDepartment of Cardiology Cardiology I, University Medical Center of the Johannes Gutenberg‐University Mainz Mainz GermanyBackground Regular exercise training represents an important modifier of arterial stiffness (AS). Therefore, sex‐specific relations between domains of physical activity (PA; commuting, domestic, and leisure‐time PA, including active sport and occupational PA) with AS were investigated. Methods and Results Stiffness index by digital photoplethysmography was investigated in 12 650 subjects from the GHS (Gutenberg Health Study). Self‐reported PA was evaluated by the “Short Questionnaire to Assess Health‐Enhancing Physical Activity” and reported as activity score peer week, being a combined measure of duration, frequency, and intensity of PA. Multivariable linear regression analysis demonstrated strong beneficial effects of repetitive activities, such as active commuting or leisure‐time PA–related walking on AS in men, but not in women. Lower AS associated with endurance training was also found among men and premenopausal women. In contrast, intense occupational PA was related to stiffer vessels in men (P<0.0001) and women (P=0.0021) in a fully adjusted model. Combination of both, performing endurance training and having stiffness index values below median, resulted in the best survival. In contrast, subjects with elevated stiffness index at baseline without any endurance activities demonstrated the worst survival. Conclusions In this population representative sample, a differential impact of domains of self‐reported PA on AS was demonstrated. Our data strengthen the importance of regular endurance PA to induce a reduction of AS, which, in turn, may improve cardiovascular prognosis. We also report deleterious effects of intense occupational PA on stiffness index, a finding that needs further confirmation by larger prospective trials.https://www.ahajournals.org/doi/10.1161/JAHA.121.020930arterial compliancemortalityphysical activitypopulation basedstiffness index |
| spellingShingle | Natalie Arnold Arne Deiseroth Omar Hahad Simon Diestelmeier Andreas Schulz Andrea Daubenbüchel Tommaso Gori Harald Binder Norbert Pfeiffer Jürgen Prochaska Manfred Beutel Karl J. Lackner Thomas Münzel Philipp S. Wild Domains of Physical Activity in Relation to Stiffness Index in the General Population Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease arterial compliance mortality physical activity population based stiffness index |
| title | Domains of Physical Activity in Relation to Stiffness Index in the General Population |
| title_full | Domains of Physical Activity in Relation to Stiffness Index in the General Population |
| title_fullStr | Domains of Physical Activity in Relation to Stiffness Index in the General Population |
| title_full_unstemmed | Domains of Physical Activity in Relation to Stiffness Index in the General Population |
| title_short | Domains of Physical Activity in Relation to Stiffness Index in the General Population |
| title_sort | domains of physical activity in relation to stiffness index in the general population |
| topic | arterial compliance mortality physical activity population based stiffness index |
| url | https://www.ahajournals.org/doi/10.1161/JAHA.121.020930 |
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