Determination of the Dissolution/Permeation and Apparent Solubility for Microencapsulated Emamectin Benzoate Using In Vitro and Ex Vivo <i>Salmo salar</i> Intestine Membranes

Determination of the Dissolution/Permeation and Apparent Solubility for Microencapsulated Emamectin Benzoate Using In Vitro and Ex Vivo <i>Salmo salar</i> Intestine Membranes

In this work, two microencapsulation techniques were used to protect and improve the absorption of emamectin benzoate (EB), which is an antiparasitic drug used to control <i>Caligus rogercresseyi</i>. EB has a low aqueous solubility, which affects its absorption in the intestine of <i...

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Bibliographic Details
Main Authors: Victoria Molina, Carlos von Plessing, Alex Romero, Sergio Benavides, José Miguel Troncoso, José Ricardo Pérez-Correa, Wendy Franco
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Pharmaceuticals
Subjects:
emamectin benzoate
dissolution/permeation
release kinetics
apparent solubility
apparent permeability
uptake
Online Access:https://www.mdpi.com/1424-8247/15/6/652

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