Interferon Genes Are Influenced by 17β-Estradiol in SLE

Interferon Genes Are Influenced by 17β-Estradiol in SLE

Recent evidence suggests the existence of a nexus between inflammatory pathways and the female sex hormone 17β-estradiol, resulting in increased interferon-stimulated genes (ISGs), autoantibodies, and dysregulation of immune cells in SLE. However, the molecular mechanisms and the effect of estradiol...

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Bibliographic Details
Main Authors:	Ram P. Singh, Bevra H. Hahn, David S. Bischoff
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-10-01
Series:	Frontiers in Immunology
Subjects:	estradiol interferon genes systemic lupus erythematosus cytokines/chemokines T cells
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.725325/full

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