Fixational eye movement waveforms in amblyopia: Characteristics of fast and slow eye movements
Fixational eye movements comprise of fast microsaccades alternating with slow inter-saccadic drifts. These physiologic eye movements play an important role in visual perception. Amblyopic patients are known to have fixation instability, particularly of the amblyopic eye. We examined eye movement ab...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Bern Open Publishing
2019-07-01
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| Series: | Journal of Eye Movement Research |
| Subjects: | |
| Online Access: | https://bop.unibe.ch/JEMR/article/view/4335 |
| _version_ | 1818380772306845696 |
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| author | Sarah Linda Kang Sinem B. Beylergil Jorge Otero-Millan Aasef Shaikh Fatema Ghasia |
| author_facet | Sarah Linda Kang Sinem B. Beylergil Jorge Otero-Millan Aasef Shaikh Fatema Ghasia |
| author_sort | Sarah Linda Kang |
| collection | DOAJ |
| description | Fixational eye movements comprise of fast microsaccades alternating with slow inter-saccadic drifts. These physiologic eye movements play an important role in visual perception. Amblyopic patients are known to have fixation instability, particularly of the amblyopic eye. We examined eye movement abnormalities that contribute to this instability. We found that fixation stability is affected by the presence of fusion maldevelopment nystagmus (FMN). However, some amblyopes can have nystagmus without nasally directed slow phases and reversal in direction of the quick phase on ocular occlusion, features seen in FMN. In patients without nystagmus, we found increased amplitude of fixational saccades and inter-saccadic drifts. We categorized amblyopia patients by type (anisometropic, strabismic, or mixed) and eye movement waveform (no nystagmus, nystagmus without FMN, and FMN). We found specific fast and slow eye movement abnormalities of the fellow and amblyopic eye during fellow, amblyopic and both eyes viewing conditions across eye movement waveforms and types of amblyopia. These eye movement abnormalities can serve as biomarkers that can predict the impact of amblyopia as measured by visual acuity and stereopsis. Evaluation of fixational eye movements in amblyopia could be important to diagnose these common eye diseases and predict treatment effectiveness. |
| first_indexed | 2024-12-14T02:23:59Z |
| format | Article |
| id | doaj.art-c95cb56b7dc04eeaa6a5a46abbd2f826 |
| institution | Directory Open Access Journal |
| issn | 1995-8692 |
| language | English |
| last_indexed | 2024-12-14T02:23:59Z |
| publishDate | 2019-07-01 |
| publisher | Bern Open Publishing |
| record_format | Article |
| series | Journal of Eye Movement Research |
| spelling | doaj.art-c95cb56b7dc04eeaa6a5a46abbd2f8262022-12-21T23:20:25ZengBern Open PublishingJournal of Eye Movement Research1995-86922019-07-0112610.16910/jemr.12.6.9Fixational eye movement waveforms in amblyopia: Characteristics of fast and slow eye movementsSarah Linda Kang0Sinem B. Beylergil1Jorge Otero-Millan2Aasef Shaikh3Fatema Ghasia4Case Western Reserve University School of MedicineCase Western Reserve University, Cleveland OHJohns Hopkins UniversityDaroff-Dell'Osso Ocular Motility Laboratory Louis Stokes VA Medical CenterCole Eye Institute Cleveland ClinicFixational eye movements comprise of fast microsaccades alternating with slow inter-saccadic drifts. These physiologic eye movements play an important role in visual perception. Amblyopic patients are known to have fixation instability, particularly of the amblyopic eye. We examined eye movement abnormalities that contribute to this instability. We found that fixation stability is affected by the presence of fusion maldevelopment nystagmus (FMN). However, some amblyopes can have nystagmus without nasally directed slow phases and reversal in direction of the quick phase on ocular occlusion, features seen in FMN. In patients without nystagmus, we found increased amplitude of fixational saccades and inter-saccadic drifts. We categorized amblyopia patients by type (anisometropic, strabismic, or mixed) and eye movement waveform (no nystagmus, nystagmus without FMN, and FMN). We found specific fast and slow eye movement abnormalities of the fellow and amblyopic eye during fellow, amblyopic and both eyes viewing conditions across eye movement waveforms and types of amblyopia. These eye movement abnormalities can serve as biomarkers that can predict the impact of amblyopia as measured by visual acuity and stereopsis. Evaluation of fixational eye movements in amblyopia could be important to diagnose these common eye diseases and predict treatment effectiveness.https://bop.unibe.ch/JEMR/article/view/4335eye movementchildrensaccadesmicrosaccadesamblyopiastrabismus |
| spellingShingle | Sarah Linda Kang Sinem B. Beylergil Jorge Otero-Millan Aasef Shaikh Fatema Ghasia Fixational eye movement waveforms in amblyopia: Characteristics of fast and slow eye movements Journal of Eye Movement Research eye movement children saccades microsaccades amblyopia strabismus |
| title | Fixational eye movement waveforms in amblyopia: Characteristics of fast and slow eye movements |
| title_full | Fixational eye movement waveforms in amblyopia: Characteristics of fast and slow eye movements |
| title_fullStr | Fixational eye movement waveforms in amblyopia: Characteristics of fast and slow eye movements |
| title_full_unstemmed | Fixational eye movement waveforms in amblyopia: Characteristics of fast and slow eye movements |
| title_short | Fixational eye movement waveforms in amblyopia: Characteristics of fast and slow eye movements |
| title_sort | fixational eye movement waveforms in amblyopia characteristics of fast and slow eye movements |
| topic | eye movement children saccades microsaccades amblyopia strabismus |
| url | https://bop.unibe.ch/JEMR/article/view/4335 |
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