The Influence of Milling on the Dissolution Performance of Simvastatin

Particle size reduction is a simple means to enhance the dissolution rate of poorly water soluble BCS-class II and IV drugs. However, the major drawback of this process is the possible introduction of process induced disorder. Drugs with different molecular arrangements may exhibit altered propertie...

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Váldodahkkit: Thomas Rades, Clare J. Strachan, Ulrike Zimper, Jaakko Aaltonen, Keith C. Gordon, Karen Krauel-Goellner
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: MDPI AG 2010-12-01
Ráidu:Pharmaceutics
Fáttát:
Liŋkkat:http://www.mdpi.com/1999-4923/2/4/419/