Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression

<p>Abstract</p> <p>The microtubule-associated protein tau (MAPT) is a pathological component of several neurodegenerative diseases and clinical dementias. Here, we have investigated the effects of a series of commercially available FDA-approved compounds and natural products on tot...

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Bibliographic Details
Main Authors: Dickey Chad A, Ash Peter, Klosak Natalia, Lee Wing C, Petrucelli Leonard, Hutton Michael, Eckman Christopher B
Format: Article
Language:English
Published: BMC 2006-07-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/1/1/6

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