Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression
<p>Abstract</p> <p>The microtubule-associated protein tau (MAPT) is a pathological component of several neurodegenerative diseases and clinical dementias. Here, we have investigated the effects of a series of commercially available FDA-approved compounds and natural products on tot...
Main Authors: | Dickey Chad A, Ash Peter, Klosak Natalia, Lee Wing C, Petrucelli Leonard, Hutton Michael, Eckman Christopher B |
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Format: | Article |
Language: | English |
Published: |
BMC
2006-07-01
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Series: | Molecular Neurodegeneration |
Online Access: | http://www.molecularneurodegeneration.com/content/1/1/6 |
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