Development of Ciprofloxacin-Loaded Bilosomes In-Situ Gel for Ocular Delivery: Optimization, In-Vitro Characterization, Ex-Vivo Permeation, and Antimicrobial Study

Development of Ciprofloxacin-Loaded Bilosomes In-Situ Gel for Ocular Delivery: Optimization, In-Vitro Characterization, Ex-Vivo Permeation, and Antimicrobial Study

Conventional eye drops are most commonly employed topically in the eye for the management of bacterial conjunctivitis. Eye drops have a low corneal residence time and 90–95% of the administered dose is eliminated from the eye by blinking and the nasolacrimal drainage system. This problem can be mini...

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Bibliographic Details
Main Authors: Omar Awad Alsaidan, Ameeduzzafar Zafar, Mohd Yasir, Sami I. Alzarea, Mohammed Alqinyah, Mohammad Khalid
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Gels
Subjects:
ocular delivery
ciprofloxacin
bilosomes
in-situ gel
HET-CAM
antimicrobial
Online Access:https://www.mdpi.com/2310-2861/8/11/687

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