Observing changes in human functioning during induced sleep deficiency and recovery periods.
Prolonged periods of sleep restriction seem to be common in the contemporary world. Sleep loss causes perturbations of circadian rhythmicity and degradation of waking alertness as reflected in attention, cognitive efficiency and memory. Understanding whether and how the human brain recovers from chr...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2021-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0255771 |
| _version_ | 1819127152543531008 |
|---|---|
| author | Jeremi K Ochab Jerzy Szwed Katarzyna Oleś Anna Bereś Dante R Chialvo Aleksandra Domagalik Magdalena Fąfrowicz Halszka Ogińska Ewa Gudowska-Nowak Tadeusz Marek Maciej A Nowak |
| author_facet | Jeremi K Ochab Jerzy Szwed Katarzyna Oleś Anna Bereś Dante R Chialvo Aleksandra Domagalik Magdalena Fąfrowicz Halszka Ogińska Ewa Gudowska-Nowak Tadeusz Marek Maciej A Nowak |
| author_sort | Jeremi K Ochab |
| collection | DOAJ |
| description | Prolonged periods of sleep restriction seem to be common in the contemporary world. Sleep loss causes perturbations of circadian rhythmicity and degradation of waking alertness as reflected in attention, cognitive efficiency and memory. Understanding whether and how the human brain recovers from chronic sleep loss is important not only from a scientific but also from a public health perspective. In this work we report on behavioral, motor, and neurophysiological correlates of sleep loss in healthy adults in an unprecedented study conducted in natural conditions and comprising 21 consecutive days divided into periods of 4 days of regular life (a baseline), 10 days of chronic partial sleep restriction (30% reduction relative to individual sleep need) and 7 days of recovery. Throughout the whole experiment we continuously measured the spontaneous locomotor activity by means of actigraphy with 1-minute resolution. On a daily basis the subjects were undergoing EEG measurements (64-electrodes with 500 Hz sampling frequency): resting state with eyes open and closed (8 minutes long each) followed by Stroop task lasting 22 minutes. Altogether we analyzed actigraphy (distributions of rest and activity durations), behavioral measures (reaction times and accuracy from Stroop task) and EEG (amplitudes, latencies and scalp maps of event-related potentials from Stroop task and power spectra from resting states). We observed unanimous deterioration in all the measures during sleep restriction. Further results indicate that a week of recovery subsequent to prolonged periods of sleep restriction is insufficient to recover fully. Only one measure (mean reaction time in Stroop task) reverted to baseline values, while the others did not. |
| first_indexed | 2024-12-22T08:07:23Z |
| format | Article |
| id | doaj.art-c961aab0d0824539829d86150e1e6f3e |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-22T08:07:23Z |
| publishDate | 2021-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-c961aab0d0824539829d86150e1e6f3e2022-12-21T18:33:07ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-01169e025577110.1371/journal.pone.0255771Observing changes in human functioning during induced sleep deficiency and recovery periods.Jeremi K OchabJerzy SzwedKatarzyna OleśAnna BereśDante R ChialvoAleksandra DomagalikMagdalena FąfrowiczHalszka OgińskaEwa Gudowska-NowakTadeusz MarekMaciej A NowakProlonged periods of sleep restriction seem to be common in the contemporary world. Sleep loss causes perturbations of circadian rhythmicity and degradation of waking alertness as reflected in attention, cognitive efficiency and memory. Understanding whether and how the human brain recovers from chronic sleep loss is important not only from a scientific but also from a public health perspective. In this work we report on behavioral, motor, and neurophysiological correlates of sleep loss in healthy adults in an unprecedented study conducted in natural conditions and comprising 21 consecutive days divided into periods of 4 days of regular life (a baseline), 10 days of chronic partial sleep restriction (30% reduction relative to individual sleep need) and 7 days of recovery. Throughout the whole experiment we continuously measured the spontaneous locomotor activity by means of actigraphy with 1-minute resolution. On a daily basis the subjects were undergoing EEG measurements (64-electrodes with 500 Hz sampling frequency): resting state with eyes open and closed (8 minutes long each) followed by Stroop task lasting 22 minutes. Altogether we analyzed actigraphy (distributions of rest and activity durations), behavioral measures (reaction times and accuracy from Stroop task) and EEG (amplitudes, latencies and scalp maps of event-related potentials from Stroop task and power spectra from resting states). We observed unanimous deterioration in all the measures during sleep restriction. Further results indicate that a week of recovery subsequent to prolonged periods of sleep restriction is insufficient to recover fully. Only one measure (mean reaction time in Stroop task) reverted to baseline values, while the others did not.https://doi.org/10.1371/journal.pone.0255771 |
| spellingShingle | Jeremi K Ochab Jerzy Szwed Katarzyna Oleś Anna Bereś Dante R Chialvo Aleksandra Domagalik Magdalena Fąfrowicz Halszka Ogińska Ewa Gudowska-Nowak Tadeusz Marek Maciej A Nowak Observing changes in human functioning during induced sleep deficiency and recovery periods. PLoS ONE |
| title | Observing changes in human functioning during induced sleep deficiency and recovery periods. |
| title_full | Observing changes in human functioning during induced sleep deficiency and recovery periods. |
| title_fullStr | Observing changes in human functioning during induced sleep deficiency and recovery periods. |
| title_full_unstemmed | Observing changes in human functioning during induced sleep deficiency and recovery periods. |
| title_short | Observing changes in human functioning during induced sleep deficiency and recovery periods. |
| title_sort | observing changes in human functioning during induced sleep deficiency and recovery periods |
| url | https://doi.org/10.1371/journal.pone.0255771 |
| work_keys_str_mv | AT jeremikochab observingchangesinhumanfunctioningduringinducedsleepdeficiencyandrecoveryperiods AT jerzyszwed observingchangesinhumanfunctioningduringinducedsleepdeficiencyandrecoveryperiods AT katarzynaoles observingchangesinhumanfunctioningduringinducedsleepdeficiencyandrecoveryperiods AT annaberes observingchangesinhumanfunctioningduringinducedsleepdeficiencyandrecoveryperiods AT danterchialvo observingchangesinhumanfunctioningduringinducedsleepdeficiencyandrecoveryperiods AT aleksandradomagalik observingchangesinhumanfunctioningduringinducedsleepdeficiencyandrecoveryperiods AT magdalenafafrowicz observingchangesinhumanfunctioningduringinducedsleepdeficiencyandrecoveryperiods AT halszkaoginska observingchangesinhumanfunctioningduringinducedsleepdeficiencyandrecoveryperiods AT ewagudowskanowak observingchangesinhumanfunctioningduringinducedsleepdeficiencyandrecoveryperiods AT tadeuszmarek observingchangesinhumanfunctioningduringinducedsleepdeficiencyandrecoveryperiods AT maciejanowak observingchangesinhumanfunctioningduringinducedsleepdeficiencyandrecoveryperiods |