Tumor cell metabolic reprogramming and hypoxic immunosuppression: driving carcinogenesis to metastatic colonization

Tumor cell metabolic reprogramming and hypoxic immunosuppression: driving carcinogenesis to metastatic colonization

A significant factor in the antitumor immune response is the increased metabolic reprogramming of immunological and malignant cells. Increasing data points to the fact that cancer metabolism affects not just cancer signaling, which is essential for maintaining carcinogenesis and survival, but also t...

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Bibliographic Details
Main Authors: Theodora Katopodi, Savvas Petanidis, Doxakis Anestakis, Charalampos Charalampidis, Ioanna Chatziprodromidou, George Floros, Panagiotis Eskitzis, Paul Zarogoulidis, Charilaos Koulouris, Christina Sevva, Konstantinos Papadopoulos, Marios Dagher, Vasileios Alexandros Karakousis, Nikolaos Varsamis, Vasiliki Theodorou, Chrysi Maria Mystakidou, Konstantinos Vlassopoulos, Stylianos Kosmidis, Nikolaos Iason Katsios, Konstantinos Farmakis, Christoforos Kosmidis
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
tumor metabolism
reprogramming
immunosuppression
metastasis
hypoxia
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1325360/full

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