RELATIONSHIP BETWEEN PSYCHOEMOTIONAL DISORDERS WITH INCREASING THICKNESS OF INTIMA-MEDIA COMPLEX AND VASCULAR MICRO INFLAMMATION DEVELOPMENT

<p><strong>Objective</strong> — to study relationship of psycho-emotional factors and indicators of intravascular microinflammation and vascular changes in healthy patients.</p><p><br /><strong>Materials and methods.</strong> To study psycho-emotional...

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Main Authors: A. P. Shavrin, B. V. Golovskoy
Format: Article
Language:Russian
Published: ABV-press 2014-07-01
Series:Klinicist
Subjects:
Online Access:http://klinitsist.abvpress.ru/index.php/Klin/article/view/79
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author A. P. Shavrin
B. V. Golovskoy
author_facet A. P. Shavrin
B. V. Golovskoy
author_sort A. P. Shavrin
collection DOAJ
description <p><strong>Objective</strong> — to study relationship of psycho-emotional factors and indicators of intravascular microinflammation and vascular changes in healthy patients.</p><p><br /><strong>Materials and methods.</strong> To study psycho-emotional status in 239 healthy patients aged 30 to 60 years, markers of inflammation (C-reactive<br />protein — CRP and cytokines — tumor necrosis factor-α — TNF-α, interleukins — IL-1, -4, - 8) and ultrasonography of the vascular wall of the common carotid artery with the definition of the thickness of intimamedia.</p><p><br /><strong>Results.</strong> In group with high levels of emotional stress significant increase in the thickness of intima media and increase in plasma concentrations<br />of markers of vascular mikrovospaleniya — CRP, IL-1, IL-8, TNF-α were showed. These correlation analysis indicated relationship between thickness of intima-media, psychoemotional factors and markers of vascular microinflamation. Calculating odds ratios revealed that thickening of the intima-media process such psycho-emotional disorders like anxiety, depression and fatigue are of great importance.</p><p><br /><strong>Conclusion.</strong> Otherwise development of latent intravascular inflammation and thickening intima-media complex of common carotid artery is registered inhealthy patients with presence of psycho-emotional disorders (depression, anxiety, fatigue).</p>
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spelling doaj.art-c9695ef405e542e1a3c50be35ad91f8e2023-01-02T11:47:35ZrusABV-pressKlinicist1818-83382014-07-0154172094RELATIONSHIP BETWEEN PSYCHOEMOTIONAL DISORDERS WITH INCREASING THICKNESS OF INTIMA-MEDIA COMPLEX AND VASCULAR MICRO INFLAMMATION DEVELOPMENTA. P. Shavrin0B. V. Golovskoy1Perm State Medical AcademyPerm State Medical Academy<p><strong>Objective</strong> — to study relationship of psycho-emotional factors and indicators of intravascular microinflammation and vascular changes in healthy patients.</p><p><br /><strong>Materials and methods.</strong> To study psycho-emotional status in 239 healthy patients aged 30 to 60 years, markers of inflammation (C-reactive<br />protein — CRP and cytokines — tumor necrosis factor-α — TNF-α, interleukins — IL-1, -4, - 8) and ultrasonography of the vascular wall of the common carotid artery with the definition of the thickness of intimamedia.</p><p><br /><strong>Results.</strong> In group with high levels of emotional stress significant increase in the thickness of intima media and increase in plasma concentrations<br />of markers of vascular mikrovospaleniya — CRP, IL-1, IL-8, TNF-α were showed. These correlation analysis indicated relationship between thickness of intima-media, psychoemotional factors and markers of vascular microinflamation. Calculating odds ratios revealed that thickening of the intima-media process such psycho-emotional disorders like anxiety, depression and fatigue are of great importance.</p><p><br /><strong>Conclusion.</strong> Otherwise development of latent intravascular inflammation and thickening intima-media complex of common carotid artery is registered inhealthy patients with presence of psycho-emotional disorders (depression, anxiety, fatigue).</p>http://klinitsist.abvpress.ru/index.php/Klin/article/view/79psycho-emotional disordersinflammationintima-media
spellingShingle A. P. Shavrin
B. V. Golovskoy
RELATIONSHIP BETWEEN PSYCHOEMOTIONAL DISORDERS WITH INCREASING THICKNESS OF INTIMA-MEDIA COMPLEX AND VASCULAR MICRO INFLAMMATION DEVELOPMENT
Klinicist
psycho-emotional disorders
inflammation
intima-media
title RELATIONSHIP BETWEEN PSYCHOEMOTIONAL DISORDERS WITH INCREASING THICKNESS OF INTIMA-MEDIA COMPLEX AND VASCULAR MICRO INFLAMMATION DEVELOPMENT
title_full RELATIONSHIP BETWEEN PSYCHOEMOTIONAL DISORDERS WITH INCREASING THICKNESS OF INTIMA-MEDIA COMPLEX AND VASCULAR MICRO INFLAMMATION DEVELOPMENT
title_fullStr RELATIONSHIP BETWEEN PSYCHOEMOTIONAL DISORDERS WITH INCREASING THICKNESS OF INTIMA-MEDIA COMPLEX AND VASCULAR MICRO INFLAMMATION DEVELOPMENT
title_full_unstemmed RELATIONSHIP BETWEEN PSYCHOEMOTIONAL DISORDERS WITH INCREASING THICKNESS OF INTIMA-MEDIA COMPLEX AND VASCULAR MICRO INFLAMMATION DEVELOPMENT
title_short RELATIONSHIP BETWEEN PSYCHOEMOTIONAL DISORDERS WITH INCREASING THICKNESS OF INTIMA-MEDIA COMPLEX AND VASCULAR MICRO INFLAMMATION DEVELOPMENT
title_sort relationship between psychoemotional disorders with increasing thickness of intima media complex and vascular micro inflammation development
topic psycho-emotional disorders
inflammation
intima-media
url http://klinitsist.abvpress.ru/index.php/Klin/article/view/79
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