RELATIONSHIP BETWEEN PSYCHOEMOTIONAL DISORDERS WITH INCREASING THICKNESS OF INTIMA-MEDIA COMPLEX AND VASCULAR MICRO INFLAMMATION DEVELOPMENT
<p><strong>Objective</strong> — to study relationship of psycho-emotional factors and indicators of intravascular microinflammation and vascular changes in healthy patients.</p><p><br /><strong>Materials and methods.</strong> To study psycho-emotional...
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Format: | Article |
Language: | Russian |
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ABV-press
2014-07-01
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Series: | Klinicist |
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Online Access: | http://klinitsist.abvpress.ru/index.php/Klin/article/view/79 |
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author | A. P. Shavrin B. V. Golovskoy |
author_facet | A. P. Shavrin B. V. Golovskoy |
author_sort | A. P. Shavrin |
collection | DOAJ |
description | <p><strong>Objective</strong> — to study relationship of psycho-emotional factors and indicators of intravascular microinflammation and vascular changes in healthy patients.</p><p><br /><strong>Materials and methods.</strong> To study psycho-emotional status in 239 healthy patients aged 30 to 60 years, markers of inflammation (C-reactive<br />protein — CRP and cytokines — tumor necrosis factor-α — TNF-α, interleukins — IL-1, -4, - 8) and ultrasonography of the vascular wall of the common carotid artery with the definition of the thickness of intimamedia.</p><p><br /><strong>Results.</strong> In group with high levels of emotional stress significant increase in the thickness of intima media and increase in plasma concentrations<br />of markers of vascular mikrovospaleniya — CRP, IL-1, IL-8, TNF-α were showed. These correlation analysis indicated relationship between thickness of intima-media, psychoemotional factors and markers of vascular microinflamation. Calculating odds ratios revealed that thickening of the intima-media process such psycho-emotional disorders like anxiety, depression and fatigue are of great importance.</p><p><br /><strong>Conclusion.</strong> Otherwise development of latent intravascular inflammation and thickening intima-media complex of common carotid artery is registered inhealthy patients with presence of psycho-emotional disorders (depression, anxiety, fatigue).</p> |
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id | doaj.art-c9695ef405e542e1a3c50be35ad91f8e |
institution | Directory Open Access Journal |
issn | 1818-8338 |
language | Russian |
last_indexed | 2024-04-11T03:10:59Z |
publishDate | 2014-07-01 |
publisher | ABV-press |
record_format | Article |
series | Klinicist |
spelling | doaj.art-c9695ef405e542e1a3c50be35ad91f8e2023-01-02T11:47:35ZrusABV-pressKlinicist1818-83382014-07-0154172094RELATIONSHIP BETWEEN PSYCHOEMOTIONAL DISORDERS WITH INCREASING THICKNESS OF INTIMA-MEDIA COMPLEX AND VASCULAR MICRO INFLAMMATION DEVELOPMENTA. P. Shavrin0B. V. Golovskoy1Perm State Medical AcademyPerm State Medical Academy<p><strong>Objective</strong> — to study relationship of psycho-emotional factors and indicators of intravascular microinflammation and vascular changes in healthy patients.</p><p><br /><strong>Materials and methods.</strong> To study psycho-emotional status in 239 healthy patients aged 30 to 60 years, markers of inflammation (C-reactive<br />protein — CRP and cytokines — tumor necrosis factor-α — TNF-α, interleukins — IL-1, -4, - 8) and ultrasonography of the vascular wall of the common carotid artery with the definition of the thickness of intimamedia.</p><p><br /><strong>Results.</strong> In group with high levels of emotional stress significant increase in the thickness of intima media and increase in plasma concentrations<br />of markers of vascular mikrovospaleniya — CRP, IL-1, IL-8, TNF-α were showed. These correlation analysis indicated relationship between thickness of intima-media, psychoemotional factors and markers of vascular microinflamation. Calculating odds ratios revealed that thickening of the intima-media process such psycho-emotional disorders like anxiety, depression and fatigue are of great importance.</p><p><br /><strong>Conclusion.</strong> Otherwise development of latent intravascular inflammation and thickening intima-media complex of common carotid artery is registered inhealthy patients with presence of psycho-emotional disorders (depression, anxiety, fatigue).</p>http://klinitsist.abvpress.ru/index.php/Klin/article/view/79psycho-emotional disordersinflammationintima-media |
spellingShingle | A. P. Shavrin B. V. Golovskoy RELATIONSHIP BETWEEN PSYCHOEMOTIONAL DISORDERS WITH INCREASING THICKNESS OF INTIMA-MEDIA COMPLEX AND VASCULAR MICRO INFLAMMATION DEVELOPMENT Klinicist psycho-emotional disorders inflammation intima-media |
title | RELATIONSHIP BETWEEN PSYCHOEMOTIONAL DISORDERS WITH INCREASING THICKNESS OF INTIMA-MEDIA COMPLEX AND VASCULAR MICRO INFLAMMATION DEVELOPMENT |
title_full | RELATIONSHIP BETWEEN PSYCHOEMOTIONAL DISORDERS WITH INCREASING THICKNESS OF INTIMA-MEDIA COMPLEX AND VASCULAR MICRO INFLAMMATION DEVELOPMENT |
title_fullStr | RELATIONSHIP BETWEEN PSYCHOEMOTIONAL DISORDERS WITH INCREASING THICKNESS OF INTIMA-MEDIA COMPLEX AND VASCULAR MICRO INFLAMMATION DEVELOPMENT |
title_full_unstemmed | RELATIONSHIP BETWEEN PSYCHOEMOTIONAL DISORDERS WITH INCREASING THICKNESS OF INTIMA-MEDIA COMPLEX AND VASCULAR MICRO INFLAMMATION DEVELOPMENT |
title_short | RELATIONSHIP BETWEEN PSYCHOEMOTIONAL DISORDERS WITH INCREASING THICKNESS OF INTIMA-MEDIA COMPLEX AND VASCULAR MICRO INFLAMMATION DEVELOPMENT |
title_sort | relationship between psychoemotional disorders with increasing thickness of intima media complex and vascular micro inflammation development |
topic | psycho-emotional disorders inflammation intima-media |
url | http://klinitsist.abvpress.ru/index.php/Klin/article/view/79 |
work_keys_str_mv | AT apshavrin relationshipbetweenpsychoemotionaldisorderswithincreasingthicknessofintimamediacomplexandvascularmicroinflammationdevelopment AT bvgolovskoy relationshipbetweenpsychoemotionaldisorderswithincreasingthicknessofintimamediacomplexandvascularmicroinflammationdevelopment |