Anxiolytic effects of NLRP3 inflammasome inhibition in a model of chronic sleep deprivation

Anxiolytic effects of NLRP3 inflammasome inhibition in a model of chronic sleep deprivation

Abstract Sleep deprivation is a form of stress that provokes both inflammatory responses and neuropsychiatric disorders. Because persistent inflammation is implicated as a physiological process in anxiety disorders, we investigated the contributions of NLRP3 inflammasome signaling to anxiety and anx...

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Bibliographic Details
Main Authors:	Chad Smith, Kyle J. Trageser, Henry Wu, Francis J. Herman, Umar Haris Iqbal, Maria Sebastian-Valverde, Tal Frolinger, Emma Zeng, Giulio Maria Pasinetti
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-01-01
Series:	Translational Psychiatry
Online Access:	https://doi.org/10.1038/s41398-020-01189-3

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