CD36-mediated podocyte lipotoxicity promotes foot process effacement
Lipid metabolism disorders lead to lipotoxicity. The hyperlipidemia-induced early stage of renal injury mainly manifests as podocyte damage. CD36 mediates fatty acid uptake and the subsequent accumulation of toxic lipid metabolites, resulting in podocyte lipotoxicity.
Bibliographic Details
| Main Authors: |
Hua Wei,
Peng Lan,
Chen Xue-mei,
Jiang XuShun,
Hu JianGuo,
Jiang Xian-Hong,
Xiang Xu,
Wan Jiangmin,
Long Yingfei,
Xiong Jianqiong,
Ma Xueyi,
Du Xiaogang |
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| Format: | Article
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| Language: | English |
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| Published: |
De Gruyter
2024-03-01
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| Series: | Open Medicine
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| Subjects: | |
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| Online Access: | https://doi.org/10.1515/med-2024-0918
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