CD36-mediated podocyte lipotoxicity promotes foot process effacement
Lipid metabolism disorders lead to lipotoxicity. The hyperlipidemia-induced early stage of renal injury mainly manifests as podocyte damage. CD36 mediates fatty acid uptake and the subsequent accumulation of toxic lipid metabolites, resulting in podocyte lipotoxicity.
Asıl Yazarlar: | Hua Wei, Peng Lan, Chen Xue-mei, Jiang XuShun, Hu JianGuo, Jiang Xian-Hong, Xiang Xu, Wan Jiangmin, Long Yingfei, Xiong Jianqiong, Ma Xueyi, Du Xiaogang |
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Materyal Türü: | Makale |
Dil: | English |
Baskı/Yayın Bilgisi: |
De Gruyter
2024-03-01
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Seri Bilgileri: | Open Medicine |
Konular: | |
Online Erişim: | https://doi.org/10.1515/med-2024-0918 |
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