<i>Mycobacterium abscessus</i> Infections in Cystic Fibrosis Individuals: A Review on Therapeutic Options
<i>Mycobacterium abscessus</i> is an opportunistic pathogen that mainly colonizes and infects cystic fibrosis patients’ lungs. <i>M. abscessus</i> is naturally resistant to many antibiotics such as rifamycin, tetracyclines and β-lactams. The current therapeutic regimens are n...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-02-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/24/5/4635 |
| Summary: | <i>Mycobacterium abscessus</i> is an opportunistic pathogen that mainly colonizes and infects cystic fibrosis patients’ lungs. <i>M. abscessus</i> is naturally resistant to many antibiotics such as rifamycin, tetracyclines and β-lactams. The current therapeutic regimens are not very effective and are mostly based on repurposed drugs used against <i>Mycobacterium tuberculosis</i> infections. Thus, new approaches and novel strategies are urgently needed. This review aims to provide an overview of the latest ongoing findings to fight <i>M. abscessus</i> infections by analyzing emerging and alternative treatments, novel drug delivery strategies, and innovative molecules. |
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| ISSN: | 1661-6596 1422-0067 |