Oft forgotten cause of diarrhea in a posttransplant setting
Chronic diarrhoea following a renal transplant is a common clinical manifestation. A large number of possible aetiologies complicate the diagnosis. Invasive testing is frequently conducted in patients with persistent or intractable diarrhoea. We discuss the case of a kidney transplant recipient who...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Indian Journal of Transplantation |
| Subjects: | |
| Online Access: | http://www.ijtonline.in/article.asp?issn=2212-0017;year=2023;volume=17;issue=4;spage=465;epage=466;aulast=Aggarwal |
| _version_ | 1827309239884840960 |
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| author | Nitin Aggarwal Puneet Chhabra Renuka Soni Shashi Naveen Priyadarshi Ranjan |
| author_facet | Nitin Aggarwal Puneet Chhabra Renuka Soni Shashi Naveen Priyadarshi Ranjan |
| author_sort | Nitin Aggarwal |
| collection | DOAJ |
| description | Chronic diarrhoea following a renal transplant is a common clinical manifestation. A large number of possible aetiologies complicate the diagnosis. Invasive testing is frequently conducted in patients with persistent or intractable diarrhoea. We discuss the case of a kidney transplant recipient who developed persistent diarrhoea with a 10-kg weight loss in a 3-week period. The patient was diagnosed with a Cryptosporidium parvum infection after stool screening for atypical organisms. Cryptosporidium has emerged as one of the most prevalent causes of infectious diarrhoea in post-renal transplant settings, particularly in endemic places such as India. The patient responded well to oral nitazoxanide. Post-renal transplant patients are in an immunocompromised state and are at significantly higher risk for getting infection-associated diarrhoea, so an approach for early stool screening for atypical organisms is advised. |
| first_indexed | 2024-04-24T19:28:05Z |
| format | Article |
| id | doaj.art-c96eb496bff6458ab31093d95422aebc |
| institution | Directory Open Access Journal |
| issn | 2212-0017 2212-0025 |
| language | English |
| last_indexed | 2024-04-24T19:28:05Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Transplantation |
| spelling | doaj.art-c96eb496bff6458ab31093d95422aebc2024-03-25T14:41:57ZengWolters Kluwer Medknow PublicationsIndian Journal of Transplantation2212-00172212-00252023-01-0117446546610.4103/ijot.ijot_28_17Oft forgotten cause of diarrhea in a posttransplant settingNitin AggarwalPuneet ChhabraRenuka SoniShashi NaveenPriyadarshi RanjanChronic diarrhoea following a renal transplant is a common clinical manifestation. A large number of possible aetiologies complicate the diagnosis. Invasive testing is frequently conducted in patients with persistent or intractable diarrhoea. We discuss the case of a kidney transplant recipient who developed persistent diarrhoea with a 10-kg weight loss in a 3-week period. The patient was diagnosed with a Cryptosporidium parvum infection after stool screening for atypical organisms. Cryptosporidium has emerged as one of the most prevalent causes of infectious diarrhoea in post-renal transplant settings, particularly in endemic places such as India. The patient responded well to oral nitazoxanide. Post-renal transplant patients are in an immunocompromised state and are at significantly higher risk for getting infection-associated diarrhoea, so an approach for early stool screening for atypical organisms is advised.http://www.ijtonline.in/article.asp?issn=2212-0017;year=2023;volume=17;issue=4;spage=465;epage=466;aulast=Aggarwalcryptosporidium parvum oocystcryptosporidium infectiondiarrhoealoss of appetiterenal transplantation |
| spellingShingle | Nitin Aggarwal Puneet Chhabra Renuka Soni Shashi Naveen Priyadarshi Ranjan Oft forgotten cause of diarrhea in a posttransplant setting Indian Journal of Transplantation cryptosporidium parvum oocyst cryptosporidium infection diarrhoea loss of appetite renal transplantation |
| title | Oft forgotten cause of diarrhea in a posttransplant setting |
| title_full | Oft forgotten cause of diarrhea in a posttransplant setting |
| title_fullStr | Oft forgotten cause of diarrhea in a posttransplant setting |
| title_full_unstemmed | Oft forgotten cause of diarrhea in a posttransplant setting |
| title_short | Oft forgotten cause of diarrhea in a posttransplant setting |
| title_sort | oft forgotten cause of diarrhea in a posttransplant setting |
| topic | cryptosporidium parvum oocyst cryptosporidium infection diarrhoea loss of appetite renal transplantation |
| url | http://www.ijtonline.in/article.asp?issn=2212-0017;year=2023;volume=17;issue=4;spage=465;epage=466;aulast=Aggarwal |
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