Gintonin regulates inflammation in human IL-1β-stimulated fibroblast-like synoviocytes and carrageenan/kaolin-induced arthritis in rats through LPAR2

Gintonin regulates inflammation in human IL-1β-stimulated fibroblast-like synoviocytes and carrageenan/kaolin-induced arthritis in rats through LPAR2

Background: In ginseng, there exists a glycolipoprotein complex with a special form of lipid LPAs called Gintonin. The purpose of this study is to show that Gintonin has a therapeutic effect on rheumatoid arthritis through LPA2 receptors. Methods: Fibroblast-like synoviocytes (FLS) were treated with...

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Bibliographic Details
Main Authors:	Mijin Kim, Bongjun Sur, Thea Villa, Jaesuk Yun, Seung Yeol Nah, Seikwan Oh
Format:	Article
Language:	English
Published:	Elsevier 2021-09-01
Series:	Journal of Ginseng Research
Subjects:	Gintonin Kaolin/carrageenan-induced arthritis Fibroblast-like synoviocytes (FLS) Lysophosphatidic acids (LPAs) Cytokines
Online Access:	http://www.sciencedirect.com/science/article/pii/S1226845321000038

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