Ihh and Runx2/Runx3 signaling interact to coordinate early chondrogenesis: a mouse model.
Endochondral bone formation begins with the development of a cartilage intermediate that is subsequently replaced by calcified bone. The mechanisms occurring during early chondrogenesis that control both mesenchymal cell differentiation into chondrocytes and cell proliferation are not clearly unders...
Main Authors: | Eun-Jung Kim, Sung-Won Cho, Jeong-Oh Shin, Min-Jung Lee, Kye-Seong Kim, Han-Sung Jung |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3562241?pdf=render |
Similar Items
-
The Transcription Factor Hand1 Is Involved In Runx2-Ihh-Regulated Endochondral Ossification.
by: Lindsay E Laurie, et al.
Published: (2016-01-01) -
Role of RUNX3 in Restriction Point Regulation
by: Jung-Won Lee, et al.
Published: (2023-02-01) -
Hedgehog Signaling Controls Chondrogenesis and Ectopic Bone Formation via the Yap-Ihh Axis
by: Qian Cong, et al.
Published: (2024-03-01) -
Runx3 Restoration Regresses K-Ras-Activated Mouse Lung Cancers and Inhibits Recurrence
by: Ja-Yeol Lee, et al.
Published: (2023-10-01) -
RUNX2-modifying enzymes: therapeutic targets for bone diseases
by: Woo-Jin Kim, et al.
Published: (2020-08-01)