Lemon juice - mediated synthesis of titanium dioxide nanoparticles with antioxidant and anti-inflammatory activity
Plant compounds such as flavonoids, terpenoids, polyphenols, enzymes, and alkaloids are used as reducing agents in eco-friendly titanium dioxide nanoparticle manufacturing. In the current investigation, titanium oxide was converted into titanium dioxide nanoparticles with the application of a lemon...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Amaltea Medical Publishing House
2023-12-01
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| Series: | Romanian Journal of Stomatology |
| Subjects: | |
| Online Access: | https://rjs.com.ro/articles/2023.4/RJS_2023_4_Art-08.pdf |
| _version_ | 1797253799955398656 |
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| author | Mary Sheloni Missier R. Mahesh S. Rajeshkumar Karthik Shunmugavelu Evangeline Cynthia Dhinakaran |
| author_facet | Mary Sheloni Missier R. Mahesh S. Rajeshkumar Karthik Shunmugavelu Evangeline Cynthia Dhinakaran |
| author_sort | Mary Sheloni Missier |
| collection | DOAJ |
| description | Plant compounds such as flavonoids, terpenoids, polyphenols, enzymes, and alkaloids are used as reducing agents in eco-friendly titanium dioxide nanoparticle manufacturing. In the current investigation, titanium oxide was converted into titanium dioxide nanoparticles with the application of a lemon extract. Amazingly, the process was also cheap, eco-friendly, and easy to implement. Seeing the white fluid change to a pale yellowish white allowed us to visually confirm that the nanoparticles had been successfully created. Transmission electron microscopy (TEM) and ultraviolet-visible spectroscopy were employed for further characterization. Nanoparticles of titanium dioxide were measured to be between 30 and 45 nm in size. In the DPPH assay, a titanium dioxide nanoparticle concentration of 50 L was shown to be optimal for antioxidant activity. The results of the bovine serum albumin denaturation experiment validated the green produced nanoparticles' dose-dependent anti-inflammatory effect. Consequently, the green synthetic titanium dioxide nanoparticles have great potential as an anti-inflammatory and antioxidant in future medicinal applications. |
| first_indexed | 2024-03-07T19:15:33Z |
| format | Article |
| id | doaj.art-c96fdf8c1ed94243a9b3e9f328048e9a |
| institution | Directory Open Access Journal |
| issn | 1843-0805 2069-6078 |
| language | English |
| last_indexed | 2024-04-24T21:39:49Z |
| publishDate | 2023-12-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Journal of Stomatology |
| spelling | doaj.art-c96fdf8c1ed94243a9b3e9f328048e9a2024-03-21T09:21:51ZengAmaltea Medical Publishing HouseRomanian Journal of Stomatology1843-08052069-60782023-12-0169419820410.37897/RJS.2023.4.8Lemon juice - mediated synthesis of titanium dioxide nanoparticles with antioxidant and anti-inflammatory activityMary Sheloni Missier0R. Mahesh1S. Rajeshkumar2Karthik Shunmugavelu3Evangeline Cynthia Dhinakaran4Doctoral School, SIMATS, Saveetha University, Chennai, Tamilnadu, India; Rajas Dental College and Hospital, Kavalkinaru, Tamilnadu, IndiaDepartment of Pedodontics, Saveetha Dental College and Hospital, SIMATS, Saveetha University, Chennai, Tamilnadu, IndiaNanobiomedicine lab, Department of Pharmacology, Saveetha Dental College and Hospital, SIMATS, Saveetha University, Chennai, Tamilnadu, IndiaDepartment of Dentistry/Oral and Maxillofacial Pathology, PSP Medical College Hospital and Research Institute, Tamilnadu, IndiaDepartment of Pathology, Sree Balaji Medical College Hospital and Research Institute, Chrompet, Chennai, Tamilnadu, IndiaPlant compounds such as flavonoids, terpenoids, polyphenols, enzymes, and alkaloids are used as reducing agents in eco-friendly titanium dioxide nanoparticle manufacturing. In the current investigation, titanium oxide was converted into titanium dioxide nanoparticles with the application of a lemon extract. Amazingly, the process was also cheap, eco-friendly, and easy to implement. Seeing the white fluid change to a pale yellowish white allowed us to visually confirm that the nanoparticles had been successfully created. Transmission electron microscopy (TEM) and ultraviolet-visible spectroscopy were employed for further characterization. Nanoparticles of titanium dioxide were measured to be between 30 and 45 nm in size. In the DPPH assay, a titanium dioxide nanoparticle concentration of 50 L was shown to be optimal for antioxidant activity. The results of the bovine serum albumin denaturation experiment validated the green produced nanoparticles' dose-dependent anti-inflammatory effect. Consequently, the green synthetic titanium dioxide nanoparticles have great potential as an anti-inflammatory and antioxidant in future medicinal applications.https://rjs.com.ro/articles/2023.4/RJS_2023_4_Art-08.pdfgreen synthesistitanium dioxide nanoparticlesantioxidantsanti-inflammatory agents |
| spellingShingle | Mary Sheloni Missier R. Mahesh S. Rajeshkumar Karthik Shunmugavelu Evangeline Cynthia Dhinakaran Lemon juice - mediated synthesis of titanium dioxide nanoparticles with antioxidant and anti-inflammatory activity Romanian Journal of Stomatology green synthesis titanium dioxide nanoparticles antioxidants anti-inflammatory agents |
| title | Lemon juice - mediated synthesis of titanium dioxide nanoparticles with antioxidant and anti-inflammatory activity |
| title_full | Lemon juice - mediated synthesis of titanium dioxide nanoparticles with antioxidant and anti-inflammatory activity |
| title_fullStr | Lemon juice - mediated synthesis of titanium dioxide nanoparticles with antioxidant and anti-inflammatory activity |
| title_full_unstemmed | Lemon juice - mediated synthesis of titanium dioxide nanoparticles with antioxidant and anti-inflammatory activity |
| title_short | Lemon juice - mediated synthesis of titanium dioxide nanoparticles with antioxidant and anti-inflammatory activity |
| title_sort | lemon juice mediated synthesis of titanium dioxide nanoparticles with antioxidant and anti inflammatory activity |
| topic | green synthesis titanium dioxide nanoparticles antioxidants anti-inflammatory agents |
| url | https://rjs.com.ro/articles/2023.4/RJS_2023_4_Art-08.pdf |
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