Maintenance of the human memory T cell repertoire by subset and tissue site

Maintenance of the human memory T cell repertoire by subset and tissue site

Abstract Background Immune-mediated protection is mediated by T cells expressing pathogen-specific T cell antigen receptors (TCR) that are maintained at diverse sites of infection as tissue-resident memory T cells (TRM) or that disseminate as circulating effector-memory (TEM), central memory (TCM),...

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Main Authors: Michelle Miron, Wenzhao Meng, Aaron M. Rosenfeld, Shirit Dvorkin, Maya Meimei Li Poon, Nora Lam, Brahma V. Kumar, Yoram Louzoun, Eline T. Luning Prak, Donna L. Farber
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Genome Medicine
Subjects:
Immunogenomics
Immunology
T cell
Immunity
Online Access:https://doi.org/10.1186/s13073-021-00918-7

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