Detection of Pyuria by Microscopic Urinalysis as a Marker of Pediatric Urinary Tract Infection
Globally, different diagnostic tests of urinary tract infection (UTI) are in clinical practices. A reliable test can increase the efficiency of the healthcare system, especially in a developing country like Nepal, reducing cost and time. Thus, we accessed the possibility of pyuria detected by micros...
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| Language: | English |
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Biotechnology Society of Nepal
2019-12-01
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| Series: | Nepal Journal of Biotechnology |
| Subjects: |
| _version_ | 1819276561630625792 |
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| author | Dhiraj Shrestha Pratigya Thapa Dinesh Bhandari Balkrishna Bhattachan Hiramani Parajuli Prakash Chaudary Vijay Kumar Sharma Pradeep Kumar Shah |
| author_facet | Dhiraj Shrestha Pratigya Thapa Dinesh Bhandari Balkrishna Bhattachan Hiramani Parajuli Prakash Chaudary Vijay Kumar Sharma Pradeep Kumar Shah |
| author_sort | Dhiraj Shrestha |
| collection | DOAJ |
| description | Globally, different diagnostic tests of urinary tract infection (UTI) are in clinical practices. A reliable test can increase the efficiency of the healthcare system, especially in a developing country like Nepal, reducing cost and time. Thus, we accessed the possibility of pyuria detected by microscopic urinalysis as a marker of pediatric UTI. The prospective study was conducted fromJuly2014 to January 2015 at Alka hospital, Lalitpur. Microscopic urinalysis of 353clean-catch urine samples was done by the wet mount method, followed by urine culture by a semi-quantitative method. We confirmed 64 (18.1%) UTI cases by culture, the gold standard for UTI diagnosis. Fever was the most common clinical manifestation in UTI cases. The sensitivity, specificity, positive predictive value and negative predictive value of pyuria detected by microscopic urinalysis to identify UTI were 50%, 70.9%, 27.6% and 86.5% respectively. In 318 febrile cases, the sensitivity, specificity, positive predictive value and negative predictive value of pyuria detected by microscopic urinalysis to identify UTI were 73.2%, 72.6%, 28.3% and 94.8% respectively. The findings suggest pyuria detected by microscopic urinalysis as not a worth while marker of pediatric UTI. But it is a trust worthy marker in febrile pediatric cases. |
| first_indexed | 2024-12-23T23:42:11Z |
| format | Article |
| id | doaj.art-c9736b974c0f4cb5844aa42c1a5d409b |
| institution | Directory Open Access Journal |
| issn | 2091-1130 2467-9313 |
| language | English |
| last_indexed | 2024-12-23T23:42:11Z |
| publishDate | 2019-12-01 |
| publisher | Biotechnology Society of Nepal |
| record_format | Article |
| series | Nepal Journal of Biotechnology |
| spelling | doaj.art-c9736b974c0f4cb5844aa42c1a5d409b2022-12-21T17:25:36ZengBiotechnology Society of NepalNepal Journal of Biotechnology2091-11302467-93132019-12-0171152010.3126/njb.v7i1.26946Detection of Pyuria by Microscopic Urinalysis as a Marker of Pediatric Urinary Tract InfectionDhiraj Shrestha0Pratigya Thapa1Dinesh Bhandari2Balkrishna Bhattachan3Hiramani Parajuli4Prakash Chaudary5Vijay Kumar Sharma6Pradeep Kumar Shah7Department of Microbiology, Shi-Gan International College of Science and Technology, Kathmandu, NepalDepartment of Microbiology, Kathmandu UpatyakaKhanepani Limited (KUKL), Kathmandu, NepalSchool of Public Health, University of Adelaide, AustraliaBiotechnology Society Nepal, Bhaktapur, NepalDepartment of Microbiology, Tri-Chandra Multiple College, Kathmandu, NepalDepartment of Microbiology, Tri-Chandra Multiple College, Kathmandu, NepalDepartment of Biochemistry, Institute of Medicine, TUTH, Kathmandu, NepalDepartment of Microbiology, Tri-Chandra Multiple College, Kathmandu, NepalGlobally, different diagnostic tests of urinary tract infection (UTI) are in clinical practices. A reliable test can increase the efficiency of the healthcare system, especially in a developing country like Nepal, reducing cost and time. Thus, we accessed the possibility of pyuria detected by microscopic urinalysis as a marker of pediatric UTI. The prospective study was conducted fromJuly2014 to January 2015 at Alka hospital, Lalitpur. Microscopic urinalysis of 353clean-catch urine samples was done by the wet mount method, followed by urine culture by a semi-quantitative method. We confirmed 64 (18.1%) UTI cases by culture, the gold standard for UTI diagnosis. Fever was the most common clinical manifestation in UTI cases. The sensitivity, specificity, positive predictive value and negative predictive value of pyuria detected by microscopic urinalysis to identify UTI were 50%, 70.9%, 27.6% and 86.5% respectively. In 318 febrile cases, the sensitivity, specificity, positive predictive value and negative predictive value of pyuria detected by microscopic urinalysis to identify UTI were 73.2%, 72.6%, 28.3% and 94.8% respectively. The findings suggest pyuria detected by microscopic urinalysis as not a worth while marker of pediatric UTI. But it is a trust worthy marker in febrile pediatric cases.febrilemarkermicroscopic urinalysispediatricpyuriauti |
| spellingShingle | Dhiraj Shrestha Pratigya Thapa Dinesh Bhandari Balkrishna Bhattachan Hiramani Parajuli Prakash Chaudary Vijay Kumar Sharma Pradeep Kumar Shah Detection of Pyuria by Microscopic Urinalysis as a Marker of Pediatric Urinary Tract Infection Nepal Journal of Biotechnology febrile marker microscopic urinalysis pediatric pyuria uti |
| title | Detection of Pyuria by Microscopic Urinalysis as a Marker of Pediatric Urinary Tract Infection |
| title_full | Detection of Pyuria by Microscopic Urinalysis as a Marker of Pediatric Urinary Tract Infection |
| title_fullStr | Detection of Pyuria by Microscopic Urinalysis as a Marker of Pediatric Urinary Tract Infection |
| title_full_unstemmed | Detection of Pyuria by Microscopic Urinalysis as a Marker of Pediatric Urinary Tract Infection |
| title_short | Detection of Pyuria by Microscopic Urinalysis as a Marker of Pediatric Urinary Tract Infection |
| title_sort | detection of pyuria by microscopic urinalysis as a marker of pediatric urinary tract infection |
| topic | febrile marker microscopic urinalysis pediatric pyuria uti |
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