CT scan screening is associated with increased distress among subjects of the APExS
<p>Abstract</p> <p>Background</p> <p>The aim of this study was to assess the psychological consequences of HRCT scan screening in retired asbestos-exposed workers.</p> <p>Methods</p> <p>A HRCT-scan screening program for asbestos-related diseases...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2010-10-01
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| Series: | BMC Public Health |
| Online Access: | http://www.biomedcentral.com/1471-2458/10/647 |
| _version_ | 1818663239548928000 |
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| author | Stoufflet Audrey Luc Amandine Maurel Marion Paris Christophe Pairon Jean-Claude Letourneux Marc |
| author_facet | Stoufflet Audrey Luc Amandine Maurel Marion Paris Christophe Pairon Jean-Claude Letourneux Marc |
| author_sort | Stoufflet Audrey |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>The aim of this study was to assess the psychological consequences of HRCT scan screening in retired asbestos-exposed workers.</p> <p>Methods</p> <p>A HRCT-scan screening program for asbestos-related diseases was carried out in four regions of France. At baseline (T1), subjects filled in self-administered occupational questionnaires. In two of the regions, subjects also received a validated psychological scale, namely the psychological consequences questionnaire (PCQ). The physician was required to provide the subject with the results of the HRCT scan at a final visit. A second assessment of psychological consequences was performed 6 months after the HRCT-scan examination (T2). PCQ scores were compared quantitatively (t-test, general linear model) and qualitatively (chi²-test, logistic regression) to screening results. Multivariate analyses were adjusted for gender, age, smoking, asbestos exposure and counseling.</p> <p>Results</p> <p>Among the 832 subjects included in this psychological impact study, HRCT-scan screening was associated with a significant increase of the psychological score 6 months after the examination relative to baseline values (8.31 to 10.08, p < 0.0001, t-test). This increase concerned patients with an abnormal HRCT-scan result, regardless of the abnormalities, but also patients with normal HRCT-scans after adjustment for age, gender, smoking status, asbestos exposure and counseling visit. The greatest increase was observed for pleural plaques (+3.60; 95%CI [+2.15;+5.06]), which are benign lesions. Detection of isolated pulmonary nodules was also associated with a less marked but nevertheless significant increase of distress (+1.88; 95%CI [+0.34;+3.42]). However, analyses based on logistic regressions only showed a close to significant increase of the proportion of subjects with abnormal PCQ scores at T2 for patients with asbestosis (OR = 1.92; 95%CI [0.97-3.81]) or with two or more diseases (OR = 2.04; 95%CI [0.95-4.37]).</p> <p>Conclusion</p> <p>This study suggests that HRCT-scan screening may be associated with increased distress in asbestos-exposed subjects. If confirmed, these results may have consequences for HRCT-scan screening recommendations.</p> |
| first_indexed | 2024-12-17T05:13:41Z |
| format | Article |
| id | doaj.art-c973b1a51f344555a23f91674bcb077c |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-12-17T05:13:41Z |
| publishDate | 2010-10-01 |
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| spelling | doaj.art-c973b1a51f344555a23f91674bcb077c2022-12-21T22:02:11ZengBMCBMC Public Health1471-24582010-10-0110164710.1186/1471-2458-10-647CT scan screening is associated with increased distress among subjects of the APExSStoufflet AudreyLuc AmandineMaurel MarionParis ChristophePairon Jean-ClaudeLetourneux Marc<p>Abstract</p> <p>Background</p> <p>The aim of this study was to assess the psychological consequences of HRCT scan screening in retired asbestos-exposed workers.</p> <p>Methods</p> <p>A HRCT-scan screening program for asbestos-related diseases was carried out in four regions of France. At baseline (T1), subjects filled in self-administered occupational questionnaires. In two of the regions, subjects also received a validated psychological scale, namely the psychological consequences questionnaire (PCQ). The physician was required to provide the subject with the results of the HRCT scan at a final visit. A second assessment of psychological consequences was performed 6 months after the HRCT-scan examination (T2). PCQ scores were compared quantitatively (t-test, general linear model) and qualitatively (chi²-test, logistic regression) to screening results. Multivariate analyses were adjusted for gender, age, smoking, asbestos exposure and counseling.</p> <p>Results</p> <p>Among the 832 subjects included in this psychological impact study, HRCT-scan screening was associated with a significant increase of the psychological score 6 months after the examination relative to baseline values (8.31 to 10.08, p < 0.0001, t-test). This increase concerned patients with an abnormal HRCT-scan result, regardless of the abnormalities, but also patients with normal HRCT-scans after adjustment for age, gender, smoking status, asbestos exposure and counseling visit. The greatest increase was observed for pleural plaques (+3.60; 95%CI [+2.15;+5.06]), which are benign lesions. Detection of isolated pulmonary nodules was also associated with a less marked but nevertheless significant increase of distress (+1.88; 95%CI [+0.34;+3.42]). However, analyses based on logistic regressions only showed a close to significant increase of the proportion of subjects with abnormal PCQ scores at T2 for patients with asbestosis (OR = 1.92; 95%CI [0.97-3.81]) or with two or more diseases (OR = 2.04; 95%CI [0.95-4.37]).</p> <p>Conclusion</p> <p>This study suggests that HRCT-scan screening may be associated with increased distress in asbestos-exposed subjects. If confirmed, these results may have consequences for HRCT-scan screening recommendations.</p>http://www.biomedcentral.com/1471-2458/10/647 |
| spellingShingle | Stoufflet Audrey Luc Amandine Maurel Marion Paris Christophe Pairon Jean-Claude Letourneux Marc CT scan screening is associated with increased distress among subjects of the APExS BMC Public Health |
| title | CT scan screening is associated with increased distress among subjects of the APExS |
| title_full | CT scan screening is associated with increased distress among subjects of the APExS |
| title_fullStr | CT scan screening is associated with increased distress among subjects of the APExS |
| title_full_unstemmed | CT scan screening is associated with increased distress among subjects of the APExS |
| title_short | CT scan screening is associated with increased distress among subjects of the APExS |
| title_sort | ct scan screening is associated with increased distress among subjects of the apexs |
| url | http://www.biomedcentral.com/1471-2458/10/647 |
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