The prevalence and clinical implication of rare germline deleterious alterations in Chinese patients with prostate cancer: A real‐world multicenter study

The prevalence and clinical implication of rare germline deleterious alterations in Chinese patients with prostate cancer: A real‐world multicenter study

Bibliographic Details
Main Authors:	Xiaochen Fei, Liancheng Fan, Wei Chen, Yiming Gong, Xinxing Du, Yanqing Wang, Yinjie Zhu, Jiahua Pan, Fangqin Wang, Wanbing Zhao, Tongtong Liu, Yining Yang, Baijun Dong, Wei Xue
Format:	Article
Language:	English
Published:	Wiley 2021-10-01
Series:	Clinical and Translational Medicine
Online Access:	https://doi.org/10.1002/ctm2.527

Similar Items

Efficacy of neoadjuvant docetaxel + cisplatin chemo-hormonal therapy versus docetaxel chemo-hormonal therapy in patients with locally advanced prostate cancer with germline DNA damage repair gene alterations
by: Chenfei Chi, et al.
Published: (2022-09-01)

Early serial circulating tumor DNA sequencing predicts the efficacy of chemohormonal therapy in patients with metastatic hormone-sensitive prostate cancer
by: Xinxing Du, et al.
Published: (2023-08-01)

Transcriptomic signature defines two subtypes of locally advanced PCa with distinct neoadjuvant therapy benefits
by: Yinjie Zhu, et al.
Published: (2023-05-01)

Extended lymphadenectomy for high-risk prostate cancer in patients with chronic lymphocytic leukemia may not be necessary: a report of two cases
by: Yinjie Zhu, et al.
Published: (2019-07-01)

Abiraterone acetate for chemotherapy-naive metastatic castration-resistant prostate cancer: a single-centre prospective study of efficacy, safety, and prognostic factors
by: Liancheng Fan, et al.
Published: (2018-12-01)

Rare deleterious germline variants and risk of lung cancer
by: Yanhong Liu, et al.
Published: (2021-02-01)

Engineering the MoS2/MXene Heterostructure for Precise and Noninvasive Diagnosis of Prostate Cancer with Clinical Specimens
by: Shaowei Xie, et al.
Published: (2023-05-01)

Single-cell analysis supports a luminal-neuroendocrine transdifferentiation in human prostate cancer
by: Baijun Dong, et al.
Published: (2020-12-01)

Germline rare deleterious variant load alters cancer risk, age of onset and tumor characteristics
by: Myvizhi Esai Selvan, et al.
Published: (2023-01-01)

Targeted next generation sequencing identifies functionally deleterious germline mutations in novel genes in early-onset/familial prostate cancer.
by: Paula Paulo, et al.
Published: (2018-04-01)

Systemic mastocytosis, in the context of a deleterious germline SDHC variant, treated with ripretinib
by: Sara Saheb Kashaf, MPhil, et al.
Published: (2023-07-01)

Incidence and Prognostic Impact of Deleterious Germline Mutations in Primary Advanced Ovarian Carcinoma Patients
by: Majdi Imterat, et al.
Published: (2023-04-01)

The Microbiome of Prostate Fluid Is Associated With Prostate Cancer
by: Xiaowei Ma, et al.
Published: (2019-07-01)

Surface-enhanced Raman spectroscopy of serum predicts sensitivity to docetaxel-based chemotherapy in patients with metastatic castration-resistant prostate cancer
by: Jianian Hu, et al.
Published: (2021-07-01)

Germline Mutations in Patients With Early-Onset Prostate Cancer
by: Tang Tang, et al.
Published: (2022-06-01)

The Diagnostic Value of PI-RADS v2.1 in Patients with a History of Transurethral Resection of the Prostate (TURP)
by: Jiazhou Liu, et al.
Published: (2022-09-01)

Deleterious effects of prepubertal corticosterone treatment on rat prostate
by: Flávia Cristina Morone Pinto, et al.
Published: (2015-06-01)

RDMAS: a web server for RNA deleterious mutation analysis
by: Zhao Dongsheng, et al.
Published: (2006-09-01)

Mainstream germline genetic testing in men with metastatic prostate cancer: design and protocol for a multicenter observational study
by: Michiel Vlaming, et al.
Published: (2022-12-01)

Persistent deleterious effects of a deleterious Wolbachia infection.
by: Perran A Ross, et al.
Published: (2020-04-01)

Clinical application of artificial neural network (ANN) modeling to predict BRCA1/2 germline deleterious variants in Chinese bilateral primary breast cancer patients
by: Yan Li, et al.
Published: (2022-11-01)

Biallelic deleterious germline SH2B3 variants cause a novel syndrome of myeloproliferation and multi‐organ autoimmunity
by: Piers Blombery, et al.
Published: (2023-05-01)

The prevalence of deleterious mutations during the domestication and improvement of soybean
by: Shichao Sun, et al.
Published: (2023-04-01)

Germline Variants of Prostate Cancer in Japanese Families.
by: Takahide Hayano, et al.
Published: (2016-01-01)

Prevalence of deleterious germline variants in risk genes including BRCA1/2 in consecutive ovarian cancer patients (AGO-TR-1).
by: Philipp Harter, et al.
Published: (2017-01-01)

Deleterious Alteration of Glia in the Brain of Alzheimer’s Disease
by: Eunyoung Kim, et al.
Published: (2020-09-01)

A novel germline BRCA2 mutation in a Chinese patient with prostate cancer sensitive to platinum chemotherapy: a case report
by: Lijuan Jiang, et al.
Published: (2021-08-01)

BRCA Germline Mutations in Prostate Cancer: The Future Is Tailored
by: Felice Crocetto, et al.
Published: (2021-05-01)

Current progress and questions in germline genetics of prostate cancer
by: William B. Isaacs, et al.
Published: (2019-01-01)

E-cadherin bridges cell polarity and spindle orientation to ensure prostate epithelial integrity and prevent carcinogenesis in vivo.
by: Xue Wang, et al.
Published: (2018-08-01)

Somatic and germline aberrations in homologous recombination repair genes in Chinese prostate cancer patients
by: Yixiao Liu, et al.
Published: (2023-03-01)

Taurine Inhibits Ferroptosis Mediated by the Crosstalk between Tumor Cells and Tumor‐Associated Macrophages in Prostate Cancer
by: Huixiang Xiao, et al.
Published: (2024-01-01)

m6A-induced repression of SIAH1 facilitates alternative splicing of androgen receptor variant 7 by regulating CPSF1
by: Lei Xia, et al.
Published: (2022-06-01)

Prognostic value of germline DNA repair gene mutations in de novo metastatic and treatment-naïve prostate cancer
by: Y. Wei, et al.
Published: (2020-07-01)

Germline ATM Mutations Detected by Somatic DNA Sequencing in Lethal Prostate Cancer
by: Rafael Grochot, et al.
Published: (2023-06-01)

Prostate Cancer: Germline Mutations in BRCA1 and BRCA2
by: Pankaja Umarane, et al.
Published: (2023-03-01)

Germline pathogenic variants in unselected Korean men with prostate cancer
by: Min-Kyung So, et al.
Published: (2022-05-01)

Circulating tumor DNA and tissue complementarily detect genomic alterations in metastatic hormone-sensitive prostate cancer
by: Bin Yang, et al.
Published: (2024-02-01)

Dexamethasone deleterious in cerebral malaria.
by: Warrell, D, et al.
Published: (1982)

Is dexamethasone deleterious in cerebral malaria?
by: Warrell, D, et al.
Published: (1983)