Regulation of the Ca2-independent phospholipase A2 in liver mitochondria by changes in the energetic state

Regulation of the Ca2-independent phospholipase A2 in liver mitochondria by changes in the energetic state

The effect of electron transport chain redox status on activity of the mitochondrial Ca2+-independent phospholipase A2 (iPLA2) has been examined. When oxidizing NAD-linked substrates, the enzyme is not active unless deenergization occurs. Uncoupler, rotenone, antimycin A, and cyanide are equally eff...

Full description

Bibliographic Details
Main Authors:	Adam J. Rauckhorst, Kimberly M. Broekemeier, Douglas R. Pfeiffer
Format:	Article
Language:	English
Published:	Elsevier 2014-05-01
Series:	Journal of Lipid Research
Subjects:	membrane potential redox status electron transport chain inhibitors
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520375027

Similar Items

REGULATION OF ARABIDOPSIS GDH2 NUCLEAR GENE EXPRESSION DEPENDS ON FUNCTIONAL STATE OF MITOCHONDRIA AND CHLOROPLASTS
by: Garnik E.Yu., et al.
Published: (2012-08-01)

Mitochondria in Diabetic Kidney Disease
by: Amna Ayesha Ahmad, et al.
Published: (2021-10-01)

The Link between Oxidative Stress, Redox Status, Bioenergetics and Mitochondria in the Pathophysiology of ALS
by: Elena Obrador, et al.
Published: (2021-06-01)

Transfer of H2O2 from Mitochondria to the endoplasmic reticulum via Aquaporin-11
by: Ilaria Sorrentino, et al.
Published: (2022-09-01)

Calmodulin antagonists effect on Ca(2+) level in the mitochondria and cytoplasm of myometrium cells
by: S. G. Shlykov, et al.
Published: (2015-10-01)

Antioxidant Role and Cardiolipin Remodeling by Redox-Activated Mitochondrial Ca<sup>2+</sup>-Independent Phospholipase A<sub>2</sub>γ in the Brain
by: Pavla Průchová, et al.
Published: (2022-01-01)

Calcium-independent phospholipases A2 and their roles in biological processes and diseases
by: Sasanka Ramanadham, et al.
Published: (2015-09-01)

Effects of Mild Excitotoxic Stimulus on Mitochondria Ca<sup>2+</sup> Handling in Hippocampal Cultures of a Mouse Model of Alzheimer’s Disease
by: Giulia Rigotto, et al.
Published: (2021-08-01)

Iridium: An option for measurement of the redox potential
by: LM Rios-Mendoza, et al.
Published: (2003-03-01)

nfluence of reducing and oxidizing compounds and of the redox potential of the medium on the biomass of Scenedesmus quadricauda (Turp.) Breb.
by: Stefan Gumiński, et al.
Published: (2014-01-01)

What happens to Bifidobacterium adolescentis and Bifidobacterium longum ssp. longum in an experimental environment with eukaryotic cells?
by: Dominika Jakubczyk, et al.
Published: (2024-02-01)

Tetrodotoxin Blockade on Canine Cardiac L-Type Ca2+ Channels Depends on pH and Redox Potential
by: Bence Hegyi, et al.
Published: (2013-06-01)

Ca2+ dependence of gluconeogenesis stimulation by glucagon at different cytosolic NAD+-NADH redox potentials
by: A.C. Marques-da-Silva, et al.
Published: (1997-07-01)

Influence of 24-Epibrassinolide on the Energetic Parameters and Early Stages of Growth and Development in Seedlings of Two Maize (<i>Zea mays</i> L.) Genotypes
by: Bojana Božilović, et al.
Published: (2023-06-01)

Structural Changes in the Acceptor Site of Photosystem II upon Ca<sup>2+</sup>/Sr<sup>2+</sup> Exchange in the Mn<sub>4</sub>CaO<sub>5</sub> Cluster Site and the Possible Long-Range Interactions
by: Faisal Hammad Mekky Koua
Published: (2019-08-01)

Redox flow batteries based on insoluble redox-active materials. A review
by: Xiao Wang, et al.
Published: (2021-03-01)

Targeting Endoplasmic Reticulum and/or Mitochondrial Ca2+ Fluxes as Therapeutic Strategy for HCV Infection
by: Rosella Scrima, et al.
Published: (2018-03-01)

Liquid-liquid extraction and transport of biologically important metal ions Li+, K+, Ca2+ and Mg2+ across an artificial liquid membrane system
by: Vani Anshumala, et al.
Published: (2011-09-01)

Functional activity of permeability transition pore in energized and deenergized rat liver mitochondria
by: O. V. Akopova, et al.
Published: (2020-12-01)

Redox Potential of Antioxidants in Cancer Progression and Prevention
by: Sajan George, et al.
Published: (2020-11-01)

Absorção de bário por plantas de arroz (Oryza sativa L.) e mobilidade em solo tratado com baritina sob diferentes condições de potencial redox
by: Erica Souto Abreu Lima, et al.
Published: (2012-01-01)

Coffeeberry Activates the CaMKII/CREB/BDNF Pathway, Normalizes Autophagy and Apoptosis Signaling in Nonalcoholic Fatty Liver Rodent Model
by: Meng-Chun Lu, et al.
Published: (2021-10-01)

The biological activity of Ocimum minimum L. flowers on redox status parameters in HCT-116 colorectal carcinoma cells
by: Jovankić Jovana V., et al.
Published: (2022-01-01)

Hepatoprotective Effects of Taraxacum officinale Root Extract on Permethrin-induced Liver Toxicity in Adult Mice
by: Fatma Ghorbel Koubaa, et al.
Published: (2020-09-01)

Effect of Copper Nanoparticles in the Diet of WKY and SHR Rats on the Redox Profile and Histology of the Heart, Liver, Kidney, and Small Intestine
by: Ewelina Cholewińska, et al.
Published: (2022-05-01)

Role of Mitochondria in Regulating Lutein and Chlorophyll Biosynthesis in Chlorella pyrenoidosa under Heterotrophic Conditions
by: Zhi-hui Liu, et al.
Published: (2018-09-01)

Association of octacosanol supplementation with redox status in patients on chronic statin therapy
by: Zrnić-Ćirić Milica, et al.
Published: (2023-01-01)

Dietary supplemental microalgal astaxanthin modulates molecular profiles of stress, inflammation, and lipid metabolism in broiler chickens and laying hens under high ambient temperatures
by: Samar A. Tolba, et al.
Published: (2020-10-01)

Convolutional neural network prediction of molecular properties for aerosol chemistry and health effects
by: Matteo Krüger, et al.
Published: (2022-10-01)

Electrochemical Monitoring of Metabolic Activity of Methane/Methanol Conversing Methylococcus Capsulatus (Bath) Cells Based on Extracellular Electron Transfer
by: Kugako SUGIMOTO, et al.
Published: (2024-02-01)

The redox potential interferes with the expression of laminin binding molecules in Bacteroides fragilis
by: Eliane de Oliveira Ferreira, et al.
Published: (2008-11-01)

A Mixture of Endocrine Disruptors and the Pesticide Roundup<sup>®</sup> Induce Oxidative Stress in Rabbit Liver When Administered under the Long-Term Low-Dose Regimen: Reinforcing the Notion of Real-Life Risk Simulation
by: Periklis Vardakas, et al.
Published: (2022-04-01)

Unbalanced redox status network as an early pathological event in congenital cataracts
by: Eloy Bejarano, et al.
Published: (2023-10-01)

Editorial: Mitochondria as a hub in cellular signaling
by: Joshua S. Stoolman, et al.
Published: (2022-08-01)

Connexin hemichannels regulate redox potential via metabolite exchange and protect lens against cellular oxidative damage
by: Yumeng Quan, et al.
Published: (2021-10-01)

Effects of cisplatin on lipid peroxidation and the glutathione redox status in the liver of male rats: The protective role of selenium
by: Trbojević Ivana S., et al.
Published: (2010-01-01)

Future Climate CO<sub>2</sub> Reduces the Tungsten Effect in Rye Plants: A Growth and Biochemical Study
by: Emad A. Alsherif, et al.
Published: (2023-05-01)

Ion selective membrane for redox flow battery, what’s next?
by: Feiran Wang, et al.
Published: (2023-09-01)

Does Methionine Status Influence the Outcome of Selenomethinione Supplementation? A Comparative Study of Metabolic and Selenium Levels in HepG2 Cells
by: Yili Hu, et al.
Published: (2022-09-01)

Properties of Selenolate-Diselenide Redox Equilibria in View of Their Thiolate-Disulfide Counterparts
by: Tamás Pálla, et al.
Published: (2023-03-01)