Hepatic myofibroblasts derived from Schistosoma mansoni-infected mice are a source of IL-5 and eotaxin: controls of eosinophil populations in vitro

Hepatic myofibroblasts derived from Schistosoma mansoni-infected mice are a source of IL-5 and eotaxin: controls of eosinophil populations in vitro

Abstract Background Hepatic myofibroblasts are relevant for pathogenesis of S. mansoni infection. In normal liver, these perisinusoidal cells are quiescent, express the lipocyte phenotype, and are located in the Disse’s space, being the major site of vitamin A storage. When activated, they convert t...

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Bibliographic Details
Main Authors: Ligia Almeida Paiva, Camila Brand, Christianne Bandeira-Melo, Patricia Torres Bozza, Marcia Cury El-Cheikh, Patricia Martins Silva, Radovan Borojevic, Sandra Aurora Chavez Perez
Format: Article
Language:English
Published: BMC 2015-11-01
Series:Parasites & Vectors
Subjects:
Liver myofibroblasts
IL-5
Eotaxin
Schistosoma mansoni
Eosinophil granulocyte
Online Access:https://doi.org/10.1186/s13071-015-1197-3

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