Comparison of retinal nerve fiber layer and macular thickness measurements with Stratus OCT and OPKO/OTI OCT devices in healthy subjects
<b>AIM:</b> To compare retinal nerve fiber layer (RNFL) and macular thickness measurements obtained with the Stratus optical coherence tomography (OCT) and OPKO/OTI OCT devices. <b>METHODS:</b> Included in the study were 59 eyes of 30 participants. All measurements for each...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2015-02-01
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| Series: | International Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325250/ |
| _version_ | 1811277527915692032 |
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| author | Ahmet Ozkok Julide Canan Umurhan Akkan Nevbahar Tamcelik Mehmet Erdogan Julide Canan Umurhan Akkan Rengin Yildirim |
| author_facet | Ahmet Ozkok Julide Canan Umurhan Akkan Nevbahar Tamcelik Mehmet Erdogan Julide Canan Umurhan Akkan Rengin Yildirim |
| author_sort | Ahmet Ozkok |
| collection | DOAJ |
| description | <b>AIM:</b> To compare retinal nerve fiber layer (RNFL) and macular thickness measurements obtained with the Stratus optical coherence tomography (OCT) and OPKO/OTI OCT devices.
<b>METHODS:</b> Included in the study were 59 eyes of 30 participants. All measurements for each eye were done on the same day with both devices. Student’s paired t-tests were used to compare the central macular thickness and RNFL measurements of the Stratus OCT and OPKO/OTI OCT. Pearson correlation was used to assess the relationship between the devices. Coefficient of variation (COV) was calculated to assess intersession repeatability.
<b>RESULTS:</b> Using both the Stratus OCT and OPKO/OTI OCT, respectively, the measured mean average RNFL thicknesses were 98.9±11.1 µm and 115.1±9.6 µm (P=0.001), and the measured mean central retinal thicknesses (CRT) were 196.2±18.8 µm and 204.5±21.1 µm (P<0.001). Measured by the two devices, the RNFL thickness values were correlated in all quadrants, as were the retinal thickness values except the inferior outer sector. COV for average RNFL and CRT thickness were 2.9% and 4.6% for Stratus OCT, and 2.1% and 4.2% for OPKO/OTI OCT, respectively.
<b>CONCLUSION:</b> We found good reproducibility of RNFL and retina thickness measurements for both Stratus OCT and OPKO/OTI OCT devices. However, even though the two OCT systems provided statistically correlated results, the values for both RNFL and macular thickness were statistically different. RNFL and macular thickness measurements with the OPKO/OTI OCT were higher than that of the Stratus OCT; therefore, the two OCT systems cannot be used interchangeably for the measurements of RNFL and macular thickness. |
| first_indexed | 2024-04-13T00:17:15Z |
| format | Article |
| id | doaj.art-c980276e1bef4056af1f49a0b41b69fd |
| institution | Directory Open Access Journal |
| issn | 2222-3959 2227-4898 |
| language | English |
| last_indexed | 2024-04-13T00:17:15Z |
| publishDate | 2015-02-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
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| series | International Journal of Ophthalmology |
| spelling | doaj.art-c980276e1bef4056af1f49a0b41b69fd2022-12-22T03:10:53ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982015-02-01819810310.3980/j.issn.2222-3959.2015.01.18Comparison of retinal nerve fiber layer and macular thickness measurements with Stratus OCT and OPKO/OTI OCT devices in healthy subjectsAhmet Ozkok0Julide Canan Umurhan Akkan1Nevbahar Tamcelik2Mehmet Erdogan3Julide Canan Umurhan Akkan4Rengin Yildirim5Department of Ophthalmology, Cerrahpasa School of Medicine, Istanbul University, Istanbul 34098, Turkey<br>Department of Ophthalmology, School of Medicine, Bezmialem Vakif University, Istanbul 34093, TurkeyDepartment of Ophthalmology, Cerrahpasa School of Medicine, Istanbul University, Istanbul 34098, Turkey<br>Department of Ophthalmology, Cerrahpasa School of Medicine, Istanbul University, Istanbul 34098, Turkey<br>Department of Ophthalmology, Cerrahpasa School of Medicine, Istanbul University, Istanbul 34098, Turkey<br>Department of Ophthalmology, Cerrahpasa School of Medicine, Istanbul University, Istanbul 34098, Turkey<br><b>AIM:</b> To compare retinal nerve fiber layer (RNFL) and macular thickness measurements obtained with the Stratus optical coherence tomography (OCT) and OPKO/OTI OCT devices. <b>METHODS:</b> Included in the study were 59 eyes of 30 participants. All measurements for each eye were done on the same day with both devices. Student’s paired t-tests were used to compare the central macular thickness and RNFL measurements of the Stratus OCT and OPKO/OTI OCT. Pearson correlation was used to assess the relationship between the devices. Coefficient of variation (COV) was calculated to assess intersession repeatability. <b>RESULTS:</b> Using both the Stratus OCT and OPKO/OTI OCT, respectively, the measured mean average RNFL thicknesses were 98.9±11.1 µm and 115.1±9.6 µm (P=0.001), and the measured mean central retinal thicknesses (CRT) were 196.2±18.8 µm and 204.5±21.1 µm (P<0.001). Measured by the two devices, the RNFL thickness values were correlated in all quadrants, as were the retinal thickness values except the inferior outer sector. COV for average RNFL and CRT thickness were 2.9% and 4.6% for Stratus OCT, and 2.1% and 4.2% for OPKO/OTI OCT, respectively. <b>CONCLUSION:</b> We found good reproducibility of RNFL and retina thickness measurements for both Stratus OCT and OPKO/OTI OCT devices. However, even though the two OCT systems provided statistically correlated results, the values for both RNFL and macular thickness were statistically different. RNFL and macular thickness measurements with the OPKO/OTI OCT were higher than that of the Stratus OCT; therefore, the two OCT systems cannot be used interchangeably for the measurements of RNFL and macular thickness.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325250/optical coherence tomographyStratus optical coherence tomographyOPKO/OTI OCTretinal nerve fiber layermacular thicknessmacular thickness |
| spellingShingle | Ahmet Ozkok Julide Canan Umurhan Akkan Nevbahar Tamcelik Mehmet Erdogan Julide Canan Umurhan Akkan Rengin Yildirim Comparison of retinal nerve fiber layer and macular thickness measurements with Stratus OCT and OPKO/OTI OCT devices in healthy subjects International Journal of Ophthalmology optical coherence tomography Stratus optical coherence tomography OPKO/OTI OCT retinal nerve fiber layer macular thickness macular thickness |
| title | Comparison of retinal nerve fiber layer and macular thickness measurements with Stratus OCT and OPKO/OTI OCT devices in healthy subjects |
| title_full | Comparison of retinal nerve fiber layer and macular thickness measurements with Stratus OCT and OPKO/OTI OCT devices in healthy subjects |
| title_fullStr | Comparison of retinal nerve fiber layer and macular thickness measurements with Stratus OCT and OPKO/OTI OCT devices in healthy subjects |
| title_full_unstemmed | Comparison of retinal nerve fiber layer and macular thickness measurements with Stratus OCT and OPKO/OTI OCT devices in healthy subjects |
| title_short | Comparison of retinal nerve fiber layer and macular thickness measurements with Stratus OCT and OPKO/OTI OCT devices in healthy subjects |
| title_sort | comparison of retinal nerve fiber layer and macular thickness measurements with stratus oct and opko oti oct devices in healthy subjects |
| topic | optical coherence tomography Stratus optical coherence tomography OPKO/OTI OCT retinal nerve fiber layer macular thickness macular thickness |
| url | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325250/ |
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