Metformin Treatment Regulates the Expression of Molecules Involved in Adiponectin and Insulin Signaling Pathways in Endometria from Women with Obesity-Associated Insulin Resistance and PCOS

Metformin Treatment Regulates the Expression of Molecules Involved in Adiponectin and Insulin Signaling Pathways in Endometria from Women with Obesity-Associated Insulin Resistance and PCOS

Polycystic ovary syndrome (PCOS) is an endocrine/metabolic disorder associated with insulin resistance (IR) and obesity. Endometria from women with PCOS present failures in insulin action, glucose uptake and signaling of insulin-sensitizing molecules, such as adiponectin, with consequences for repro...

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Bibliographic Details
Main Authors: Maria Lorena Oróstica, Isis Astorga, Francisca Plaza-Parrochia, Cristian Poblete, Rodrigo Carvajal, Víctor García, Carmen Romero, Margarita Vega
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
metformin
adiponectin
insulin resistance
obesity
PCOS
endometrium
Online Access:https://www.mdpi.com/1422-0067/23/7/3922

Internet

https://www.mdpi.com/1422-0067/23/7/3922

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