Hippocampal microglial activation triggers a neurotoxic-specific astrocyte response and mediates etomidate-induced long-term synaptic inhibition
Abstract Background Accumulating evidence has highlighted the importance of microglial and astrocyte responses in the pathological development of postoperative cognitive dysfunction (POCD). However, the mechanisms involved are not well understood. Methods A perioperative neurocognitive disorders (PN...
Main Authors: | Dongliang Li, Mingming Chen, Tao Meng, Jianchun Fei |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-04-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12974-020-01799-0 |
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