A coordinate deregulation of microRNAs expressed in mucosa adjacent to tumor predicts relapse after resection in localized colon cancer

A coordinate deregulation of microRNAs expressed in mucosa adjacent to tumor predicts relapse after resection in localized colon cancer

Abstract Up to 20% of colorectal cancer (CRC) node-negative patients develop loco-regional or distant recurrences within 5 years from surgery. No predictive biomarker able to identify the node-negative subjects at high risk of relapse after curative treatment is presently available. Forty-eight loca...

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Bibliographic Details
Main Authors: Angela Grassi, Lisa Perilli, Laura Albertoni, Sofia Tessarollo, Claudia Mescoli, Emanuele D. L. Urso, Matteo Fassan, Massimo Rugge, Paola Zanovello
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Molecular Cancer
Subjects:
microRNAs
localized colon cancer
relapse
predictive markers
adjacent mucosa
Online Access:http://link.springer.com/article/10.1186/s12943-018-0770-8

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